Document Detail

Outpatient multimodality management of large submucosal myomas using transvaginal radiofrequency myolysis.
MedLine Citation:
PMID:  24882599     Owner:  NLM     Status:  Publisher    
BACKGROUND: Submucosal myomas are associated with subfertility and infertility, and hysteroscopic myomectomy is the most commonly recommended treatment for these tumors. However, large submucosal leiomyomas with deep intramural positioning cannot be treated by this method. In the present retrospective observational study, we report our experience with a group of patients who underwent transvaginal radiofrequency myolysis (RFM) with or without combined hysteroscopy for large submucosal leiomyomas with a substantial intramural portion, with an emphasis on the safety and efficacy of this procedure in the outpatient department.
METHODS: Twenty-four patients with for large submucosal leiomyomas with a substantial intramural portion were enrolled to undergo stepwise RFM treatment. Additional hysteroscopic myomectomy was performed in 6 patients at 3-6 months after the RFM. Myoma volumes were measured by three-dimensional ultrasonography before RFM and 1, 3, 6, 12, 24 months postoperatively. Symptoms severity was assessed using the Uterine Fibroids Symptom and Quality of Life Questionnaire and health-related quality of life (HRQoL) questionnaire.
RESULTS: The total volume reduction rate 24 months postoperatively was 84.2%. Symptom severity and HRQoL scores showed significant improvements 12 months after RFM.
CONCLUSIONS: Radiofrequency myolysis with or without hysteroscopy is an effective treatment modality for patients with large myomas with deep intramural positioning, and it seems safe for all patients with submucosal myoma-related symptoms.
Hyun Hee Cho; Mee Ran Kim; Jang Heub Kim
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-29
Journal Detail:
Title:  Journal of minimally invasive gynecology     Volume:  -     ISSN:  1553-4669     ISO Abbreviation:  J Minim Invasive Gynecol     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-6-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235322     Medline TA:  J Minim Invasive Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 AAGL. Published by Elsevier Inc. All rights reserved.
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