| Outpatient lumbar epidural corticosteroid injection in the management of sciatica. | |
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MedLine Citation:
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PMID: 3408828 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The value of epidural injections of corticosteroid as an outpatient treatment of sciatica has been hitherto uncertain. An epidural injection of 80 mg methylprednisolone in 10 ml physiological saline was compared with an interspinous injection of 2 ml physiological saline in a double blind fashion amongst 39 outpatients. Significant differences of pain relief were seen between the two groups within 2 weeks. This benefit disappeared for six (35%) patients within 6 months of treatment although 11 (65%) successfully treated subjects had sustained improvement up to this time. Outpatient epidural injections of corticosteroid are thus a useful short-term means of relieving pain in sciatica but probably have little effect on the long-term natural history of symptoms. Factors associated with a failure to respond to epidural steroid injections are discussed. |
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Authors:
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M G Ridley; G H Kingsley; T Gibson; R Grahame |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: British journal of rheumatology Volume: 27 ISSN: 0263-7103 ISO Abbreviation: Br. J. Rheumatol. Publication Date: 1988 Aug |
Date Detail:
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Created Date: 1988-10-05 Completed Date: 1988-10-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8302415 Medline TA: Br J Rheumatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 295-9 Citation Subset: AIM; IM |
Affiliation:
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Rheumatology Unit, Guy's Hospital, London. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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administration & dosage*,
therapeutic use Adult Female Humans Injections, Epidural Male Middle Aged Outpatients Sciatica / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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