Document Detail


Outline of proteins and signaling pathways involved in Heart Failure.
MedLine Citation:
PMID:  23228350     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Heart failure (HF) is a condition with high mortality worldwide characterized by persistent progression. Myocardial hypertrophy is a dominant feature during the early stage of HF. The development of HF is a complex process related to a series of physiologic and molecular factors. Although the treatment of HF has been changed during the past century, the knowledge on its molecular mechanism is still very limited. The review herein tries to touch the molecular basis underlying HF and discusses the relevance between HF and other diseases such as thrombosis. Furthermore, we believe that the global alterations during progression of HF revealed by high content screening techniques may facilitate our understanding on HF, and thereby the development of new therapeutics with less side effect.
Authors:
Qun Bi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-13
Journal Detail:
Title:  Current protein & peptide science     Volume:  -     ISSN:  1875-5550     ISO Abbreviation:  Curr. Protein Pept. Sci.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-12-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100960529     Medline TA:  Curr Protein Pept Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
College of Life Sciences, Peking University, Beijing 100871, P. R. China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Functions of MAPR (membrane-associated progesterone receptor) family members as heme/steroid-binding...
Next Document:  Epidemiologic characteristics, serotypes, and antimicrobial susceptibilities of invasive Streptococc...