| Outcomes and side effects of duplex-guided sclerotherapy in the treatment of great saphenous veins with 1% versus 3% polidocanol foam: results of a randomized controlled trial with 1-year follow-up. | |
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MedLine Citation:
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PMID: 17338683 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Eighty subjects were treated with either 1 or 3% polidocanol foam to compare the efficacy and adverse sequelae of each concentration of polidocanol foam. OBJECTIVE: The objective was to compare the effects of two different concentrations of polidocanol foam. MATERIAL AND METHODS: During a 6-month period, we treated 80 consecutive patients with primary incompetent great saphenous veins in combination with saphenofemoral junction incompetence. These patients were treated with foam of either 1 or 3% polidocanol. Duplex analyses were made before treatment and in follow-up visits to determine the presence or absence of reflux. RESULTS: After 1 year, there was a clinically relevant difference in percentage of patients with occlusion of the treated great saphenous vein between both groups: 69.5% in the 1% foam group versus 80.1% in the 3% foam group; however, this difference was not statistically significant (p=.249). After 1 year of follow-up, patients in the 3% polidocanol group noticed a larger cosmetic improvement than patients in the 1% group. CONCLUSIONS: In the treatment of primary incompetent greater saphenous veins, 3% polidocanol foam seems to be more effective than 1% polidocanol foam. The side effects were approximately similar in both groups. |
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Authors:
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Roeland P M Ceulen; Yolande I J M Bullens-Goessens; Sebastien J A Pi-VAN DE Venne; Patty J Nelemans; Joep C J M Veraart; Anja Sommer |
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Publication Detail:
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Type: Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Volume: 33 ISSN: 1076-0512 ISO Abbreviation: Dermatol Surg Publication Date: 2007 Mar |
Date Detail:
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Created Date: 2007-03-06 Completed Date: 2007-04-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9504371 Medline TA: Dermatol Surg Country: United States |
Other Details:
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Languages: eng Pagination: 276-81 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University Hospital Maastricht, Maastricht, The Netherlands. rce@sder.azm.nl |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Follow-Up Studies Humans Male Middle Aged Polyethylene Glycols / administration & dosage* Saphenous Vein / ultrasonography Sclerotherapy / methods* Tissue Adhesives / administration & dosage* Venous Insufficiency / drug therapy* |
| Chemical | |
Reg. No./Substance:
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0/Polyethylene Glycols; 0/Tissue Adhesives; 9002-92-0/polidocanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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