Document Detail

Outcomes of quintuplet pregnancies.
MedLine Citation:
PMID:  11789084     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To review the obstetric and perinatal complications associated with quintuplet pregnancies in the United States. STUDY DESIGN: The databases of two large support groups for higher order multiple gestations, the Triplet Connection and Mothers of Super Twins, were accessed for quintuplet pregnancies. Each record contained information regarding maternal demographics, obstetric complications and perinatal outcomes. The data were analyzed by the Student t test and chi 2 test as indicated, with a P value < .05 for significance. RESULTS: Complete data were obtained for 36 quintuplet pregnancies. Preterm labor complicated all pregnancies. Six pregnancies delivered prior to 24 weeks' gestation, with no surviving infants. In the remaining 30 pregnancies, the mean gestational age at delivery was 28.9 weeks (SD +/- 2.0). There were trends toward later gestational ages at delivery in pregnancies with prophylactic cerclage placement and among multiparous women; however, these trends were not statistically significant. The perinatal mortality rate for the entire sample was 253/1,000. When adjusted for pregnancies delivered beyond 24 weeks' gestation, the perinatal mortality rate was 83/1,000. Minor and major neonatal morbidity affected 20% (26/132) and 10% (13/132) of quintuplet neonates, respectively. CONCLUSION: Quintuplet pregnancies are associated with high rates of obstetric complications and significant perinatal morbidity and mortality.
K Francois; A Alperin; J P Elliott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  46     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2002-01-14     Completed Date:  2002-03-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1047-51     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Arizona Health Sciences Center, Tucson, Arizona, USA.
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MeSH Terms
Gestational Age
Infant Mortality*
Infant, Newborn
Obstetric Labor, Premature*
Pregnancy Complications / epidemiology*
Pregnancy Outcome
Retrospective Studies

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