| Outcomes of newly diagnosed idiopathic generalized epilepsy syndromes in a non-pediatric setting. | |
| | |
MedLine Citation:
|
PMID: 17295717 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: The prognosis of idiopathic generalized epilepsy syndromes (IGES) in the adult setting may vary from that in children owing to differences in genetic, environmental and lifestyle factors. METHODS: All patients diagnosed with epilepsy at the Epilepsy Unit, Western Infirmary, Glasgow, between 1981 and 2001 were reviewed. RESULTS: Of 890 patients, 118 (13%) met the criteria for IGES. Outcomes were known for 103, 66 (64%) of whom achieved remission. The responder rate with sodium valproate was superior (66% vs 45%, P = 0.073) to that with lamotrigine (LTG) particularly in patients with juvenile myoclonic epilepsies (75% vs 39%, P = 0.014). History of febrile seizures was the only factor associated with reduced likelihood of remission (P = 0.032) CONCLUSIONS: Idiopathic generalized epilepsy syndromes constituted 13% of cases in a largely adult cohort of newly diagnosed epilepsy, most of whom achieved remission usually with a single antiepileptic drug. History of febrile seizures was associated with a poorer outcome. |
| | |
Authors:
|
R Mohanraj; M J Brodie |
Related Documents
:
|
10768307 - Effectiveness, tolerability, and safety of topiramate in children with partial-onset se... 12423387 - Hyperventilation-induced high-amplitude rhythmic slowing with altered awareness: a vide... 2239277 - Increased interleukin-1 (il-1) production from lps-stimulated peripheral blood monocyte... 11221157 - Neurological manifestations of children with systemic lupus erythematosus. 15890117 - Assessing parents' perception of children's risk for recreational water illnesses. 19692717 - Association of attention-deficit/hyperactivity disorder and atopic eczema modified by s... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta neurologica Scandinavica Volume: 115 ISSN: 0001-6314 ISO Abbreviation: Acta Neurol. Scand. Publication Date: 2007 Mar |
Date Detail:
|
Created Date: 2007-02-13 Completed Date: 2007-04-03 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370336 Medline TA: Acta Neurol Scand Country: Denmark |
Other Details:
|
Languages: eng Pagination: 204-8 Citation Subset: IM |
Affiliation:
|
Department of Neurology, Hope Hospital, Salford, Lancashire, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Anticonvulsants / administration & dosage, therapeutic use* Drug Therapy, Combination Epilepsy, Generalized / diagnosis*, drug therapy* Female Follow-Up Studies Great Britain Humans Male Outpatient Clinics, Hospital Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Anticonvulsants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lamotrigine in idiopathic epilepsy - increased risk of cardiac death?
Next Document: Regulation of platelet-derived growth factor signaling pathway by ethanol, nicotine, or both in mous...