| Outcomes in patients with Goodpasture's syndrome and hydrocarbon exposure. | |
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MedLine Citation:
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PMID: 12380899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Goodpasture's Syndrome has been associated with hydrocarbon exposure. No study has examined outcomes in these patients. All reported cases of Goodpasture's Syndrome and hydrocarbon exposure were identified using MEDLINE and was analyzed for factors related to outcomes. A total of 43 cases were identified since 1969. The mean age of patients was 28 years old. There was a slight predilection for males (60%) when analyzing gender. Various types of hydrocarbons were identified and the duration of exposure varied from minutes to years. A majority of patients (86%) had pulmonary hemorrhage and antiglomerular basement membrane antibodies (AGBM) (92%). Patients were treated with immunosuppressive agents. The only significant statistical correlation was female patients with hydrocarbon exposure were younger. There was no correlation between age, gender, duration of exposure, presence of pulmonary hemorrhage or AGBM, or other risk factors and outcome. The relationship between hydrocarbon exposure and Goodpasture's Syndrome remains unclear since only 6% of cases in the literature had exposure. Even though most patients survived, no factor studied affected outcome making it difficult to predict prognosis in these patients. |
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Authors:
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Mrugeshkumar K Shah |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Renal failure Volume: 24 ISSN: 0886-022X ISO Abbreviation: Ren Fail Publication Date: 2002 Sep |
Date Detail:
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Created Date: 2002-10-16 Completed Date: 2003-02-25 Revised Date: 2008-05-21 |
Medline Journal Info:
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Nlm Unique ID: 8701128 Medline TA: Ren Fail Country: United States |
Other Details:
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Languages: eng Pagination: 545-55 Citation Subset: IM |
Affiliation:
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Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA 70012, USA. mrugshah@hotmail.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anti-Glomerular Basement Membrane Disease / chemically induced*, therapy* Female Humans Hydrocarbons / adverse effects* Infant Male Middle Aged Outcome Assessment (Health Care)* |
| Chemical | |
Reg. No./Substance:
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0/Hydrocarbons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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