| Outcomes in children treated for persistent bacterial bronchitis. | |
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MedLine Citation:
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PMID: 17105776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Persistent bacterial bronchitis (PBB) seems to be under-recognised and often misdiagnosed as asthma. In the absence of published data relating to the management and outcomes in this patient group, a review of the outcomes of patients with PBB attending a paediatric respiratory clinic was undertaken. METHODS: A retrospective chart review was undertaken of 81 patients in whom a diagnosis of PBB had been made. Diagnosis was based on the standard criterion of a persistent, wet cough for >1 month that resolves with appropriate antibiotic treatment. RESULTS: The most common reason for referral was a persistent cough or difficult asthma. In most of the patients, symptoms started before the age of 2 years, and had been present for >1 year in 59% of patients. At referral, 59% of patients were receiving asthma treatment and 11% antibiotics. Haemophilus influenzae and Streptococcus pneumoniae were the most commonly isolated organisms. Over half of the patients were completely symptom free after two courses of antibiotics. Only 13% of patients required > or =6 courses of antibiotics. CONCLUSION: PBB is often misdiagnosed as asthma, although the two conditions may coexist. In addition to eliminating a persistent cough, treatment may also prevent progression to bronchiectasis. Further research relating to both diagnosis and treatment is urgently required. |
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Authors:
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Deirdre Donnelly; Anita Critchlow; Mark L Everard |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-11-14 |
Journal Detail:
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Title: Thorax Volume: 62 ISSN: 0040-6376 ISO Abbreviation: Thorax Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2006-12-25 Completed Date: 2007-02-08 Revised Date: 2010-09-15 |
Medline Journal Info:
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Nlm Unique ID: 0417353 Medline TA: Thorax Country: England |
Other Details:
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Languages: eng Pagination: 80-4 Citation Subset: IM |
Affiliation:
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Paediatric Respiratory Unit, Sheffield Children's Hospital, Western Bank, Sheffield S10 2TH, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amoxicillin
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therapeutic use* Anti-Bacterial Agents / therapeutic use* Bronchiectasis / prevention & control Bronchitis / drug therapy*, microbiology Child Child, Preschool Clavulanic Acid / therapeutic use* Cohort Studies Cough / drug therapy*, microbiology Humans Retrospective Studies Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 26787-78-0/Amoxicillin; 58001-44-8/Clavulanic Acid |
| Comments/Corrections | |
Comment In:
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Thorax. 2007 Oct;62(10):922-3; author reply 923
[PMID:
17909192
]
Thorax. 2007 Oct;62(10):921; author reply 921-2 [PMID: 17909191 ] |
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