Document Detail

Outcomes of fat injection laryngoplasty in unilateral vocal cord paralysis.
MedLine Citation:
PMID:  20479375     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To analyze outcomes following fat injection laryngoplasty in patients with unilateral vocal cord paralysis. DESIGN: Longitudinal outcomes evaluation study. SETTING: Tertiary referral voice center. PATIENTS: Thirty-three consecutive patients with unilateral vocal cord paralysis undergoing autologous fat injection laryngoplasty with preoperative and serial postoperative follow-up at Chang Gung Memorial Hospital, Taipei, Taiwan. INTERVENTION: Autologous fat injection laryngoplasty. MAIN OUTCOME MEASURES: Voice laboratory measurements, Voice Outcome Survey, and 36-item Short Form Health Survey. RESULTS: Except for the physical functioning dimension of global health, voice-related subjective outcomes and acoustic variables of the patients significantly improved after surgery (P < .05). Compared with population norms, the mean (SD) scores of patients were inferior on the 36-item Short Form Health Survey dimensions of physical functioning (80.7 [22.3] vs 90.2 [17.4]) and role functioning-physical problems (65.0 [36.2] vs 80.2 [36.2]). Overall, 88.9% (24 of 27) of the patients were satisfied with their surgery. CONCLUSIONS: Fat injection laryngoplasty seems to be effective in enhancing acoustic and quality of life outcomes in patients with unilateral vocal cord paralysis. The effect is sustainable over 12 months.
Tuan-Jen Fang; Hsueh-Yu Li; Richard E Gliklich; Ya-Hui Chen; Pa-Chun Wang; Hsiu-Feng Chuang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of otolaryngology--head & neck surgery     Volume:  136     ISSN:  1538-361X     ISO Abbreviation:  Arch. Otolaryngol. Head Neck Surg.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8603209     Medline TA:  Arch Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  457-62     Citation Subset:  AIM; IM    
Department of Otolaryngology, Chang Gung Memorial Hospital, Keelung, Taiwan.
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MeSH Terms
Adipose Tissue*
Longitudinal Studies
Middle Aged
Quality of Life
Speech Acoustics
Statistics, Nonparametric
Treatment Outcome
Vocal Cord Paralysis / therapy*

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