|Outcomes of aortic valve repair according to valve morphology and surgical techniques.|
|PMID: 22761124 Owner: NLM Status: MEDLINE|
|OBJECTIVES: The aim of this study was to assess the impact of aortic valve morphology and different surgical aortic valve repair techniques on long-term clinical outcomes.
METHODS: Between February 2003 and May 2010, 216 patients with aortic insufficiency underwent aortic valve repair in our institution. Ages ranged between 26 and 82 years (mean 53 ± 15 years). Aortic valve dysfunctions, according to functional classification, were: type I in 55 patients (25.5%), type II in 126 (58.3%) and type III in 35 (16.2%). Sixty-six patients (27.7%) had a bicuspid valve. Aortic valve repair techniques included sub-commissural plasty in 138 patients, plication in 84, free-edge reinforcement in 80, resection of raphe plus re-suturing in 40 and the chordae technique in 52. Concomitant surgical procedures were CABG in 22 (10%) patients, mitral valve repair in 12 (5.5%), aortic valve-sparing re-implantation in 78 (36%) and ascending aorta replacement in 69 (32%). Mean follow-up was 42 ± 16 months and was 100% complete.
RESULTS: There were six early deaths (2.7%). Overall late survival was 91.5% (18 late deaths). There were 15 (6.9%) late cardiac-related deaths. NYHA functional class was ≤ II in all patients. At follow-up, 28 (14.5%) patients had recurrent aortic insufficiency ≥ grade II. The freedom from valve-related events was significantly different between bicuspid and tricuspid valve implantation (P < 0.01), between type I + II and type III (P < 0.001) dysfunction and between the chordae technique and plication, compared to free-edge reinforcement (P < 0.01). Statistically-significant differences were found between patients who underwent aortic valve repair plus root re-implantation, compared to those who underwent isolated aortic valve repair (P = 0.02).
CONCLUSIONS: Aortic valve repair including aortic annulus stabilization is a safe surgical option with either tricuspid or bicuspid valves; even more so if associated with root re-implantation. Patients with calcified bicuspid valves have poor results.
|Khalil Fattouch; Giacomo Murana; Sebastiano Castrovinci; Giuseppe Nasso; Claudia Mossuto; Egle Corrado; Giovanni Ruvolo; Giuseppe Speziale|
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|Type: Comparative Study; Journal Article Date: 2012-07-03|
|Title: Interactive cardiovascular and thoracic surgery Volume: 15 ISSN: 1569-9285 ISO Abbreviation: Interact Cardiovasc Thorac Surg Publication Date: 2012 Oct|
|Created Date: 2012-09-19 Completed Date: 2013-02-08 Revised Date: 2013-10-11|
Medline Journal Info:
|Nlm Unique ID: 101158399 Medline TA: Interact Cardiovasc Thorac Surg Country: England|
|Languages: eng Pagination: 644-50 Citation Subset: IM|
|Department of Cardiac Surgery, University of Palermo, Palermo, Italy. firstname.lastname@example.org|
|APA/MLA Format Download EndNote Download BibTex|
Aged, 80 and over
Aorta / surgery
Aortic Valve / abnormalities, surgery*, ultrasonography
Aortic Valve Insufficiency / complications, mortality, surgery*, ultrasonography
Blood Vessel Prosthesis Implantation
Calcinosis / complications, mortality, surgery*, ultrasonography
Cardiac Valve Annuloplasty* / adverse effects, mortality
Chordae Tendineae / surgery
Coronary Artery Bypass
Mitral Valve / surgery
Proportional Hazards Models
Suture Techniques* / adverse effects, mortality
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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