| Outcomes after primary percutaneous coronary intervention in octogenarians and nonagenarians with ST segment elevation myocardial infarction from the western denmark heart registry. | |
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MedLine Citation:
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PMID: 22887706 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Elderly patients with ST-segment elevation myocardial infarction (STEMI) constitute a particular risk group in relation to primary percutaneous coronary intervention (PPCI). OBJECTIVE: We examined the proportion of octogenarians and nonagenarians undergoing PPCI in Western Denmark, and their short- and long-term mortality rates. METHODS: From 2002 to 2009 all consecutive patients ≥80 years with STEMI treated with PPCI were identified in the population based Western Denmark Heart Registry. Cox regression analysis was used to compute hazard ratios, controlling for potential confounding. RESULTS: A total of 1,322 elderly (1,213 octogenarians and 109 nonagenarians), corresponding to 11.6% of the total PPCI treated STEMI population, were treated with PPCI between 2002 and 2009. The annual proportion of octogenarians referred for PPCI increased from n=52 (6.2%) in 2002 to n=172 (11.8%) in 2009 (p<0.01), while it remained unchanged in nonagenarians: n=6 (0.6%) in 2002 to n=13 (0.8%) in 2009 (p=ns). For octogenarians and nonagenarians 30-day mortality was 17.2% vs. 25.8% (log rank p=0.028), 1-year mortality was 27.6% vs. 32.5% (log rank p=0.18) and 5-year mortality 53.6% vs. 57.3% (log-rank p=0.087), respectively. Adjusted 30-day HR=1.59 (95% confidence interval=CI 1.07-2.36), 1-year HR=1.34 (CI 0.95-1.90) and 5-year mortality HR=1.39 (CI 1.04-1.85), was higher in nonagenarians compared to octogenarians. CONCLUSION: The annual proportion of octogenarians with STEMI treated with PPCI doubled from 2002 to 2009, while the proportion of nonagenarians remained unchanged. Although nonagenarians had the highest short- and long-term mortality, we found the outcome acceptable with a 5-year survival of more than 40% in both groups. © 2012 Wiley Periodicals, Inc. |
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Authors:
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Lisbeth Antonsen; Lisette Okkels Jensen; Christian Juhl Terkelsen; Hans-Henrik Tilsted; Anders Junker; Michael Maeng; Knud Noerregaard Hansen; Jens Flensted Lassen; Leif Thuesen; Per Thayssen |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-6 |
Journal Detail:
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Title: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions Volume: - ISSN: 1522-726X ISO Abbreviation: Catheter Cardiovasc Interv Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100884139 Medline TA: Catheter Cardiovasc Interv Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Wiley Periodicals, Inc. |
Affiliation:
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Department of Cardiology, Odense University Hospital, Odense, Denmark. dr_lissie@hotmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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