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Outcomes Associated with Carotid Pseudo-Occlusion.
MedLine Citation:
PMID:  21411990     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Purpose: We tested the hypothesis that patients with carotid pseudo-occlusion (PO) have a different prognosis from those with carotid artery stenosis (CS) without PO. Materials and Methods: 500 patients were examined for CS by cerebral angiography; those with severe CS ≥70% (CS group) or with PO (PO group) were enrolled in this study. The primary endpoint was defined as the combined endpoint of the occurrence of stroke, myocardial infarction, or death. Patients without any events were censored at 60 months. We followed patients for the occurrence and date of primary endpoints and compared clinical characteristics and outcomes between the PO group and the CS group. Results: We enrolled 337 patients (281 men, 56 women, mean age: 70.4 years, mean follow-up period: 32.0 months), of whom 303 (89.9%) were allocated to the CS group while 34 (10.1%) were allocated to the PO group. The rate of diabetes mellitus in the PO group (55.9%) tended to be higher than in the CS group (39.9%). According to Kaplan-Meier analysis, the PO group suffered from the primary outcome more frequently than the CS group. The occurrence of the primary outcome was also associated with older age, peripheral arterial disease and a history of myocardial infarction. Multivariate analysis indicated that patients in the PO group had a significantly poorer outcome compared with those in the CS group (p = 0.013). Conclusion: Patients in the PO group more frequently had neurological and cardiac events or died compared with those in the CS group.
Authors:
Toshiyasu Ogata; Masahiro Yasaka; Yuka Kanazawa; Yoshiyuki Wakugawa; Tooru Inoue; Kotaro Yasumori; Takanari Kitazono; Yasushi Okada
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-16
Journal Detail:
Title:  Cerebrovascular diseases (Basel, Switzerland)     Volume:  31     ISSN:  1421-9786     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100851     Medline TA:  Cerebrovasc Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  494-498     Citation Subset:  -    
Copyright Information:
Copyright © 2011 S. Karger AG, Basel.
Affiliation:
Department of Cerebrovascular Medicine, Center and Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
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