Document Detail


Outcome predictors in pregnant opiate and polydrug users.
MedLine Citation:
PMID:  10485309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A retrospective case note study of 93 women was performed in order to assess the effect of maternal factors on neonatal outcome in a group of women attending a specialist clinic for pregnant drug users. There were no significant differences in outcome for chaotic drug users compared with non-chaotic drug users, or for cocaine users compared with non-cocaine using drug users. Women who reduced their methadone dose during pregnancy delivered babies of significantly higher birth weight than those whose methadone dose remained the same or increased (median 3027 g, range 1780-3629 g vs 2645 g, range 580-3720 g). Women who abused benzodiazepines during pregnancy produced babies of significantly lower birth weight than those women who did not use benzodiazepines (median 2100 g, range 580-3520 g vs 2767 g, range 1530-3720 g). The results of this study give healthcare staff evidence to use in encouraging drug-using women to avoid benzodiazepines during pregnancy and to reduce their methadone dosage. The treatment received from a specialist clinic may mitigate against some of the other recognised effects of drug use during pregnancy.
Authors:
J E McCarthy; C Siney; N J Shaw; S M Ruben
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  158     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-10-21     Completed Date:  1999-10-21     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  748-9     Citation Subset:  IM    
Affiliation:
Liverpool Womens Hospital, UK.
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MeSH Terms
Descriptor/Qualifier:
Benzodiazepines / adverse effects
Birth Weight / drug effects*
Female
Humans
Infant, Low Birth Weight
Infant, Newborn
Methadone / adverse effects
Narcotics / adverse effects*
Pregnancy
Pregnancy Complications*
Pregnancy Outcome
Retrospective Studies
Substance-Related Disorders*
Chemical
Reg. No./Substance:
0/Narcotics; 12794-10-4/Benzodiazepines; 76-99-3/Methadone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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