Document Detail

Outcome of infants born at 21-28 weeks' gestation in an inner-city hospital over an eight-year period.
MedLine Citation:
PMID:  17302519     Owner:  NLM     Status:  MEDLINE    
Outcome of all live births at 21-28 weeks' gestation (GA) and/or <1250 g birth weight (BW) over an eight-year period were reviewed and compared with other outcome data. Causes of mortality were ascertained for all deaths. Significant morbidities were reviewed among <25 weeks GA and/or <800 g survivors over a two-year period. NICU admissions log book, monthly morbidity-mortality reports, medical records and autopsy findings were used to obtain outcome data. A total of 23,046 infants were born alive during the study period, including 339 (1.47%) at 21-28 weeks or <1250 g. Eighty of the 339 (23.6%) died. Of these 80 deaths 32.5% were extremely immature, 15% died from RDS, 15% from infection, 10% from pulmonary hemorrhage and 8% had lethal malformations. Survival outcome in each weight group except <500 g were similar to that reported by the Pediatrix Medical Group (2003-04) and 2002 US National Vital Statistics. Of the extremely low gestational age infants, 79% survived to discharge, and among these, the incidence of serious neuro-morbidity, severe chronic lung disease or retinopathy of prematurity requiring treatment was 52%; 18.5% had more than one major morbidity.
Muhammad Aslam; Zehra Panjvani; Ben K Rajegowda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  35     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2007  
Date Detail:
Created Date:  2007-03-08     Completed Date:  2007-06-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  151-4     Citation Subset:  IM    
Department of Pediatrics/Neonatology, Lincoln Medical and Mental Health Center, Bronx, NY, USA.
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MeSH Terms
Hospitals, Urban
Infant Mortality*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / epidemiology*
New York City / epidemiology
Pregnancy Trimester, Second
Socioeconomic Factors
Urban Population

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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