Document Detail


Outcome of induction of labour using maternal characteristics, ultrasound assessment and biochemical state of the cervix.
MedLine Citation:
PMID:  20230317     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To assess pre-induction sonographic, digital examination and biochemical changes in the cervix to predict induction outcome.
METHODS: Transvaginal and abdominal scans were performed in 460 women at 37-41 weeks of gestation to determine cervical length (CL), posterior cervical angle (PCA) and foetal occipital position. The Bishop Score (BS) and the absence/presence of phosphorylated form of insulin-like growth factor-binding protein-1 (phIGFBP-1) in cervical secretions were assessed. Independent parameters significantly associated with a vaginal delivery were identified.
RESULTS: A total of 340 (73.9%) women achieved a vaginal delivery following induction. Multivariate analysis indicated that significant independent predictors of vaginal delivery were CL (adjusted odds ratio [AOR]: 0.59, 95% confidence interval [CI]: 0.45-0.79), PCA (AOR: 1.89, 95% CI: 1.09-3.28) and multiparae (AOR: 10.02, 95% CI: 5.10-19.69). For a specificity of 75%, the sensitivity for prediction of vaginal delivery using the BS, the CL and the multivariate model using the identified significant independent predictors were 37.1, 46.8 and 68%, respectively.
CONCLUSION: The combination of sonographic assessment of the cervix and maternal characteristics was superior to the either BS or CL alone in the prediction of the induction outcome. Inclusion of the absence/presence of phIGFBP-1 did not further improve induction outcome.
Authors:
Chun Wai Cheung; Tak Yeung Leung; Daljit Singh Sahota; Oi Ka Chan; Lin Wai Chan; Tak Yuen Fung; Tze Kin Lau
Related Documents :
9271837 - Risk factors for primary postpartum haemorrhage. a case control study.
20505947 - Influence of the mode of delivery on maternal and neonatal outcomes: a comparison betwe...
3480677 - Cervical priming and labor induction with vaginal application of 3 mg pge2 in supposito...
10755767 - Maternal height as a risk factor for caesarean section due to failure to progress in la...
9203477 - The contribution of urethrocystoscopy to evaluation of lower urinary tract dysfunction ...
14687237 - Association of the lewis genotype with cardiovascular risk factors and subclinical caro...
Publication Detail:
Type:  Journal Article     Date:  2010-03-16
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  23     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  1406-12     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Maternal serum ADAM12 in Chinese women undergoing screening for aneuploidy in the first trimester.
Next Document:  An assessment of vascularity and flow intensity of the placenta in normal pregnancy and pre-eclampsi...