Document Detail

Outcome following staphylococcal peritonitis.
MedLine Citation:
PMID:  10809246     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Staphylococcus spp predominate as the causative pathogen of continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis.This study evaluated the difference in morbidity and mortality between peritonitis caused by S. aureus and coagulase-negative staphylococci (CoNS). DESIGN: Prospective observational study. SETTING: A single regional dialysis unit in a teaching hospital. PATIENTS: Thirty-seven patients had S. aureus peritonitis and 65 patients had CoNS peritonitis between July 1990 and November 1995. MAIN OUTCOME MEASURES: Using the first recorded episode of peritonitis, survival analysis was performed for time to (1) death, (2) removal of peritoneal dialysis catheter, and (3) change to hemodialysis. Abdominal complications were recorded for the first and subsequent episodes. RESULTS: No difference in time to death was demonstrated for the two groups (p = 0.79), although two deaths that occurred during therapy for peritonitis were attributable to S. aureus infection. In addition, 5 patients developed serious abdominal complications related to an episode of S. aureus peritonitis. Patients with S. aureus peritonitis had a shorter time to both peritoneal dialysis catheter removal (p = 0.004) and change to hemodialysis (p = 0.014). The change in mode of dialysis was independent of catheter loss. CONCLUSION: This study highlights the serious nature of S. aureus peritonitis and confirms the need for effective preventive measures against infection by this pathogen.
S J Peacock; P A Howe; N P Day; D W Crook; C G Winearls; A R Berendt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  20     ISSN:  0896-8608     ISO Abbreviation:  Perit Dial Int     Publication Date:    2000 Mar-Apr
Date Detail:
Created Date:  2000-08-01     Completed Date:  2000-08-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  215-9     Citation Subset:  IM    
Nuffield Department of Pathology and Bacteriology, The Oxford Radcliffe Hospital NHS Trust, Oxford, United Kingdom.
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MeSH Terms
Aged, 80 and over
Middle Aged
Peritoneal Dialysis
Peritonitis / drug therapy,  microbiology*,  mortality
Prospective Studies
Staphylococcal Infections*
Staphylococcus / enzymology
Survival Rate
Treatment Outcome
Reg. No./Substance:

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