| Outcome of duodenum-preserving resection of the head of the pancreas for intraductal papillary-mucinous neoplasm. | |
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MedLine Citation:
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PMID: 15237258 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The standard surgical procedure for intraductal papillary-mucinous neoplasm of the pancreatic head is pylorus-preserving pancreatoduodenectomy. A less extensive resection may be justified because most intraductal papillary-mucinous neoplasms are benign or of low-grade malignancy. AIMS AND METHODS: The outcome of duodenum-preserving pancreatic head resection with preservation of the main bile duct was evaluated retrospectively in 13 patients with a branch-type intraductal papillary-mucinous neoplasm in the head of the pancreas and with a median (range) follow-up of 60.0 (0.3-99.5) months. RESULTS: Post-operative complications included anastomotic leakage (n=3), bile duct perforation (n=1), intra-abdominal bleeding (n=3), delayed gastric emptying (n=2) and death (n=2). All the resection margins were clear of tumour on histological examination. Ten of 11 patients maintained over 90% of their pre-operative body weight. Glucose tolerance improved in 4 of 11 evaluable patients, was unchanged in 6 and worsened in 1 patient. Biliary scintigraphy showed that bile flow was delayed compared with that before surgery (8.8 +/- 1.1 vs. 19.6 +/- 4.6 min; p = 0.03). Neither recurrence nor metastasis was observed. CONCLUSION: The results of duodenum-preserving pancreatic head resection for branch duct-type intraductal papillary-mucinous neoplasm were satisfactory and provided a good quality of life. |
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Authors:
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Satoshi Hirano; Satoshi Kondo; Yoshiyasu Ambo; Eiichi Tanaka; Toshiaki Morikawa; Shunichi Okushiba; Hiroyuki Katoh |
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Publication Detail:
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Type: Journal Article Date: 2004-06-30 |
Journal Detail:
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Title: Digestive surgery Volume: 21 ISSN: 0253-4886 ISO Abbreviation: Dig Surg Publication Date: 2004 |
Date Detail:
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Created Date: 2004-07-26 Completed Date: 2004-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8501808 Medline TA: Dig Surg Country: Switzerland |
Other Details:
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Languages: eng Pagination: 242-5 Citation Subset: IM |
Copyright Information:
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Copyright 2004 S. Karger AG, Basel |
Affiliation:
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Department of Surgical Oncology, Division of Cancer Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan. satto@med.hokudai.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma, Mucinous
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surgery* Adenocarcinoma, Papillary / surgery* Carcinoma, Pancreatic Ductal / surgery* Digestive System Surgical Procedures / methods Duodenum Female Follow-Up Studies Humans Male Middle Aged Pancreatic Neoplasms / surgery* Postoperative Complications / epidemiology Quality of Life Time Factors Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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