| Outcome of delivery and cause-specific mortality and severe morbidity in early infancy: a Kenyan District Hospital birth cohort. | |
| | |
MedLine Citation:
|
PMID: 13677381 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
It has proven very difficult to determine the causes of early infant mortality and morbidity in Africa. We undertook a two-year, prospective birth cohort study in a rural Kenyan District Hospital to estimate cause-specific mortality and severe morbidity in infants too young to gain benefit from routine immunization approaches. A total of 2,359 infants eligible for the cohort were delivered. Of these, 136 (6%) were stillborn and 77 (3.5%) subsequently died. Prematurity (34%), birth asphyxia (27%), and infection (18.5%) were the predominant causes of death in the first 98 days of life, although infection accounted for 36% of all life-threatening illness episodes in the same period. The data suggest that health system constraints are likely to impede programmatic efforts to reduce early infant mortality and morbidity, and that infection prevention measures offer some promise for mortality reduction. Assessing the cost effectiveness of the latter, particularly for very specific interventions such as further maternal vaccination, will require very large trials. |
| | |
Authors:
|
Mike English; Ann Muhoro; Maurice Aluda; Sam Were; Amanda Ross; Norbert Peshu |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The American journal of tropical medicine and hygiene Volume: 69 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2003 Aug |
Date Detail:
|
Created Date: 2003-09-17 Completed Date: 2003-10-06 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
|
Languages: eng Pagination: 228-32 Citation Subset: AIM; IM |
Affiliation:
|
Centre for Geographic Medicine Research-Coast, Kenya Medical Research Institute, Kilifi, Kenya. menglish@kilifi.mimcom.net |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cause of Death Cohort Studies Female Fetal Death Hospitals, District Humans Infant Mortality* Infant, Newborn Kenya / epidemiology Male Medically Underserved Area Pregnancy Pregnancy Outcome* Prenatal Care Prospective Studies Rural Health Services |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Short report: limited and short-lasting humoral response in Taenia solium: seropositive households c...
Next Document: Determination of extrarenal plasma clearance and hepatic uptake of technetium-99m-mercaptoacetyltrig...