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Outcome of breast lesions detected at screening ultrasonography.
MedLine Citation:
PMID:  22591758     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To assess the final outcome of breast lesions detected during screening ultrasonography (US) and categorized by BI-RADS final assessment. MATERIALS AND METHODS: During a 1-year period, 3817 consecutive asymptomatic women with negative findings at both clinical breast examinations and mammography underwent bilateral whole breast US and BI-RADS categories were provided for US-detected breast lesions. The reference standard was a combination of histology and US follow-up (≥12 months), and the final outcomes of 1192 US-detected lesions were analyzed. RESULTS: Of 904 category 2 lesions, 890 remained stable for 12-60 months. Biopsies of 14 lesions revealed no malignancies (NPV=100%). Of 247 category 3 lesions, 232 remained stable for 12-60 months. Biopsies of 15 lesions revealed 2 malignancies, which were diagnosed within 6 months of the index examination and were node negative (NPV=99.2%). Of 41 category 4 lesions, biopsies of 38 lesions revealed 5 malignancies (PPV=12.2%), and 3 remained stable for 37-51 months. No US-detected lesion was classified as category 5. CONCLUSION: The rates of malignancy for US-detected BI-RADS categories 2, 3, and 4 lesions were 0%, 0.8%, and 12.2%, respectively. The final assessment of US BI-RADS categorization showed it to be an appropriate predictor of malignancy for screening US-detected breast lesions.
Authors:
Seung Ja Kim; Jung Min Chang; Nariya Cho; Se-Yeong Chung; Wonshik Han; Woo Kyung Moon
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-14
Journal Detail:
Title:  European journal of radiology     Volume:  -     ISSN:  1872-7727     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Ireland Ltd.
Affiliation:
Department of Radiology, Seoul Metropolitan Government Seoul National University, Boramae Medical Center, 41, Boramae-gil, Dongjak-gu, Seoul 156-707, Republic of Korea.
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