| Outcome of antenatally diagnosed fetal anterior abdominal wall defects from a single tertiary centre. | |
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MedLine Citation:
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PMID: 18987479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The aim of this study was to review the outcome of all cases of antenatally diagnosed anterior abdominal wall defects at a single tertiary centre. METHOD: 41 cases from the database of the Centre of Fetal Care at Queen Charlotte's and Chelsea Hospital in London from 2000 to 2005 were reviewed and both obstetric and neonatal data were collected. RESULTS: 25 cases were exomphalos (61%), 9 were gastroschisis (22%), 6 were body stalk anomaly (15%) and 1 case was cloacal exstrophy (2%). 17 cases (41%) were associated with other major malformations and 4 (10%) were aneuploid. There was 1 case of intrauterine death (2%). Termination of pregnancy was performed in 24 cases (63%). Of the cases that continued (exomphalos and gastroschisis), all babies survived surgery and were discharged home. CONCLUSIONS: This study demonstrates a high termination rate for fetuses diagnosed with anterior abdominal wall defects. However, the surgical outcome for euploid neonates with isolated exomphalos or gastroschisis appears to be good. Babies with gastroschisis required a longer period of parenteral feeding compared with babies with exomphalos. These infants however had a longer duration of hospitalization. |
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Authors:
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C Arnaoutoglou; L Pasquini; R Abel; S Kumar |
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Publication Detail:
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Type: Journal Article Date: 2008-11-06 |
Journal Detail:
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Title: Fetal diagnosis and therapy Volume: 24 ISSN: 1421-9964 ISO Abbreviation: Fetal. Diagn. Ther. Publication Date: 2008 |
Date Detail:
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Created Date: 2009-01-30 Completed Date: 2009-04-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: Switzerland |
Other Details:
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Languages: eng Pagination: 416-9 Citation Subset: IM |
Copyright Information:
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Copyright 2008 S. Karger AG, Basel. |
Affiliation:
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Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Wall
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abnormalities* Abortion, Induced / statistics & numerical data Adult Bladder Exstrophy / diagnosis, epidemiology, surgery Databases, Factual Female Gastroschisis / diagnosis*, epidemiology*, surgery Hernia, Umbilical / diagnosis, epidemiology, surgery Humans Infant, Newborn Length of Stay / statistics & numerical data London / epidemiology Pregnancy Pregnancy Outcome / epidemiology* Prenatal Diagnosis* Retrospective Studies Young Adult |
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