Document Detail

Outcome of antenatally diagnosed fetal anterior abdominal wall defects from a single tertiary centre.
MedLine Citation:
PMID:  18987479     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of this study was to review the outcome of all cases of antenatally diagnosed anterior abdominal wall defects at a single tertiary centre. METHOD: 41 cases from the database of the Centre of Fetal Care at Queen Charlotte's and Chelsea Hospital in London from 2000 to 2005 were reviewed and both obstetric and neonatal data were collected. RESULTS: 25 cases were exomphalos (61%), 9 were gastroschisis (22%), 6 were body stalk anomaly (15%) and 1 case was cloacal exstrophy (2%). 17 cases (41%) were associated with other major malformations and 4 (10%) were aneuploid. There was 1 case of intrauterine death (2%). Termination of pregnancy was performed in 24 cases (63%). Of the cases that continued (exomphalos and gastroschisis), all babies survived surgery and were discharged home. CONCLUSIONS: This study demonstrates a high termination rate for fetuses diagnosed with anterior abdominal wall defects. However, the surgical outcome for euploid neonates with isolated exomphalos or gastroschisis appears to be good. Babies with gastroschisis required a longer period of parenteral feeding compared with babies with exomphalos. These infants however had a longer duration of hospitalization.
C Arnaoutoglou; L Pasquini; R Abel; S Kumar
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Publication Detail:
Type:  Journal Article     Date:  2008-11-06
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  24     ISSN:  1421-9964     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:  2008  
Date Detail:
Created Date:  2009-01-30     Completed Date:  2009-04-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  416-9     Citation Subset:  IM    
Copyright Information:
Copyright 2008 S. Karger AG, Basel.
Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, London, UK.
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MeSH Terms
Abdominal Wall / abnormalities*
Abortion, Induced / statistics & numerical data
Bladder Exstrophy / diagnosis,  epidemiology,  surgery
Databases, Factual
Gastroschisis / diagnosis*,  epidemiology*,  surgery
Hernia, Umbilical / diagnosis,  epidemiology,  surgery
Infant, Newborn
Length of Stay / statistics & numerical data
London / epidemiology
Pregnancy Outcome / epidemiology*
Prenatal Diagnosis*
Retrospective Studies
Young Adult

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