| Outcome after heroin overdose and cardiopulmonary resuscitation. | |
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MedLine Citation:
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PMID: 16987342 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The survival of heroin overdose patients resuscitated from cardiac arrest is reported to be poor. The aim of our study was to investigate the outcome and characteristics of survivors after cardiac arrest caused by heroin overdose. METHODS: This was a retrospective study in a medium-sized city (population, 560,000). Between 1 January 1997 and 31 December 2000, there were 94 combined cardiac arrests caused by acute drug poisonings. The main outcome measure was survival to discharge. RESULTS: Cardiopulmonary resuscitation was attempted in 19 heroin overdose patients (group A) and in 53 patients with cardiac arrest caused by other poisonings (group B). Three (16%) vs. six (11%) patients were discharged alive (group A vs. B, respectively). The survivors in group A had an Emergency Medical Service (EMS)-witnessed cardiac arrest or the Emergency Dispatching Centre was called before the arrest occurred. There was no statistically significant difference between the two groups in terms of survival. Survivors in both groups suffered from acute renal failure (two), hypoglycaemia (four) and hypothermia (three). CONCLUSION: Survival after cardiac arrest caused by heroin overdose is possible if the arrest is EMS witnessed or the Emergency Dispatching Centre is called before the cardiac arrest occurs. In comparison with cardiac arrests caused by other poisonings, there was no difference in survival. The incidence and mechanism of hypoglycaemia should be examined in further studies. |
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Authors:
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J J Boyd; M J Kuisma; A O Alaspää; E Vuori; J V Repo; T T Randell |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta anaesthesiologica Scandinavica Volume: 50 ISSN: 0001-5172 ISO Abbreviation: Acta Anaesthesiol Scand Publication Date: 2006 Oct |
Date Detail:
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Created Date: 2006-09-21 Completed Date: 2007-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370270 Medline TA: Acta Anaesthesiol Scand Country: England |
Other Details:
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Languages: eng Pagination: 1120-4 Citation Subset: IM |
Affiliation:
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Helsinki Emergency Medical Service, Helsinki University Central Hospital, Helsinki, Finland. james.boyd@hus.fi |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cardiac Output / physiology Cardiopulmonary Resuscitation* Emergency Medical Services Epinephrine / therapeutic use Female Finland / epidemiology Heart Arrest / chemically induced, therapy Heroin / poisoning* Heroin Dependence / epidemiology Humans Hypoglycemia / chemically induced Male Middle Aged Narcotics / poisoning* Overdose Rhabdomyolysis / chemically induced Survival Vasoconstrictor Agents / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Narcotics; 0/Vasoconstrictor Agents; 51-43-4/Epinephrine; 561-27-3/Heroin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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