| Outcome after acute ischemic stroke (AIS) in older patients: Effects of age, neurological deficit severity and blood pressure (BP) variations. | |
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MedLine Citation:
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PMID: 21145118 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The goal of this study was to examine the relationship between BP variations and neurological deficit outcome in old-old patients after AIS. Fifty-four patients (66-96 years), admitted consecutively for stroke were assessed, using a non-invasive BP monitoring (NIBPM), measuring mean systolic (SBP) and diastolic (DBP) blood pressure and their variation between days 1 and 7. Neurological assessment and cognitive function were evaluated using the NIH stroke Scale (NIHSS) and the short portable mental status Questionnaire (SPMSQ), respectively. Functional status was assessed using the modified Rankin scale (RS) and the Barthel index (BI). NIHSS on the 1st day positively correlated with SPMSQ score and with BI on day 21. The NIHSS variation (ΔNIHSS) between days 21 and 1 negatively correlated with mean 24-h BP change between days 7 and 1 (r=-0.59 for DBP and r=-0.54 for SBP; p<0.001). Age, severity of stroke at admission, history of hypertension, atrial fibrillation (AF) and BP levels at admission were not correlated to ΔNIHSS. An inverse correlation between the decrease of 24-h BP within the first week and ΔNIHSS suggests prudence in lowering BP in the acute phase of stroke in elderly. |
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Authors:
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Valter Giantin; Andrea Semplicini; Alessandro Franchin; Matteo Simonato; Kareen Baccaglini; Francesca Attanasio; Elena D Toffanello; Enzo Manzato |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-12-7 |
Journal Detail:
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Title: Archives of gerontology and geriatrics Volume: - ISSN: 1872-6976 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214379 Medline TA: Arch Gerontol Geriatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Medical and Surgical Sciences, Division of Geriatrics, Ospedale Giustinianeo (2° piano), via Giustiniani 2, I-35100 Padova, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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