Document Detail


Outcome after Introduction of Complete Mesocolic Excision for Colon Cancer Is Similar for Open and Laparoscopic Surgical Treatments.
MedLine Citation:
PMID:  24022524     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: Complete mesocolic excision (CME) and a high (apical) vascular tie may improve oncologic outcome after surgery for colon cancer. Our primary aim was to emulate a previous national result of 73.8% overall survival (OS) with both the open and laparoscopic techniques. Methods: A prospective study of radical colon cancer was initiated in a Norwegian community teaching hospital in 2007 and comprised a consecutive group of 251 patients with TNM stages I-III that had surgery according to the CME principle. Oncological outcome was assessed as OS, disease-free survival (DFS) and cancer-specific survival (CSS), as well as time to recurrence (TTR), using Cox regression analysis. Results: In-hospital mortality was 3.6%, 2.3% for laparoscopic surgery and 4.9% for open management. Significantly more patients in the open CME group developed complications in the short term (p < 0.001). Twelve or more lymph nodes were retrieved from 82.9% (208/251) of the specimens. Overall 3-year OS was 84.5%, DFS 77.4%, CSS 91.5% and TTR 86.8%. The surgical approach was not a significant predictor for any of the survival parameters. Conclusions: There was no survival difference between open and laparoscopic CME colonic resections, and the present OS improved from a previous OS from 2000. © 2013 S. Karger AG, Basel.
Authors:
Kristian E Storli; Karl Søndenaa; Bjørg Furnes; Geir Egil Eide
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-9-10
Journal Detail:
Title:  Digestive surgery     Volume:  30     ISSN:  1421-9883     ISO Abbreviation:  Dig Surg     Publication Date:  2013 Sep 
Date Detail:
Created Date:  2013-9-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501808     Medline TA:  Dig Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  317-327     Citation Subset:  -    
Affiliation:
Department of Surgery, Haraldsplass Deaconess Hospital, University of Bergen, Bergen, Norway.
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