Document Detail


Outcome of ablation for sustained focal atrial tachycardia in patients with and without a history of atrial fibrillation.
MedLine Citation:
PMID:  15717150     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: The aim of this study was to determine the long-term results of ablation for sustained focal atrial tachycardia in patients with and without a history of atrial fibrillation. METHODS: A history of atrial fibrillation was documented in 25 of 111 patients (23%) with focal atrial tachycardias. We studied the results of focal ablation during a follow-up of 27 +/- 22 months. RESULTS: Enlargement of left atrium (Odds ratio 2.99) and septal origin of the atrial focus (Odds ratio 5.68) were independent predictors of coexisting atrial fibrillation. Patients with a septal origin of the focal atrial tachycardia were older (62 vs. 54 years) and had a higher rate of structural heart disease than patients with a non-septal site of origin (51 vs. 29%). A higher rate of atrial fibrillation was found in patients with anteroseptal (56%), midseptal (50%) and posteroseptal (36%) atrial tachycardias than in patients with focal atrial tachycardias arising from the crista terminalis (9%), the tricuspid (12%) and mitral annulus (0%), the ostia of thoracic veins (17%) and other right atrial (27%) and left atrial free wall sites (10%). During the follow-up, atrial fibrillation was documented in 3% of patients without preexisting atrial fibrillation. In patients with focal atrial tachycardia and a history of atrial fibrillation, at least one episode of atrial fibrillation was documented during follow-up in 64% of patients, but 60% of patients reported marked symptomatic improvement. CONCLUSION: An increased rate of coexisting atrial fibrillation was found in patients with a septal origin of focal atrial tachycardia. Ablation of the focal atrial tachycardia may eliminate both arrhythmias, but patients with a history of atrial fibrillation may still be prone to recurrences of atrial fibrillation after focal ablation.
Authors:
Christopher Reithmann; Uwe Dorwarth; Michael Fiek; Tomas Matis; Thomas Remp; Gerhard Steinbeck; Ellen Hoffmann
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  12     ISSN:  1383-875X     ISO Abbreviation:  J Interv Card Electrophysiol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-02-17     Completed Date:  2005-05-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  35-43     Citation Subset:  IM    
Affiliation:
Medzomoscje Klinik 1, Klinikum Grosshadern, universität München, Germany. Christopher.Reithmann@med.uni-muenchen.de
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / complications*
Body Surface Potential Mapping
Catheter Ablation*
Chi-Square Distribution
Female
Humans
Male
Middle Aged
Statistics, Nonparametric
Tachycardia, Supraventricular / complications*,  surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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