Document Detail


Outcome of Glenn anastomosis for heterotaxy syndrome with single ventricle.
MedLine Citation:
PMID:  16714703     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A retrospective study was undertaken of 157 patients who underwent a Glenn anastomosis between January 1996 and May 2001. Of these, 33 had heterotaxy syndrome: 20 males and 13 females, with a mean age of 1.26 +/- 2.8 years. Twenty-five had right atrial isomerism and 5 had left isomerism. A common atrioventricular valve was found in 24 patients, 18 had bilateral superior venae cavae, and 18 had anomalous pulmonary venous return. Repair was carried out in 8 patients with anomalous pulmonary venous return, and pulmonary artery augmentation was performed in 11. Compared to the 124 patients who had a Glenn operation for single ventricle without heterotaxy, there were significantly longer durations of mechanical ventilation, intensive care unit stay, and inotropic support, as well as higher mortality in the heterotaxy group. Heterotaxy syndrome with single ventricle still has a high rate of morbidity and mortality. Patients with severe atrioventricular valve regurgitation are at risk of early death. Complete Fontan circulation may not be possible in all patients, and Glenn anastomosis may be their final palliation.
Authors:
Mohammed Koudieh; E Dean McKenzie; Charles D Fraser
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Asian cardiovascular & thoracic annals     Volume:  14     ISSN:  1816-5370     ISO Abbreviation:  Asian Cardiovasc Thorac Ann     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-22     Completed Date:  2008-05-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503417     Medline TA:  Asian Cardiovasc Thorac Ann     Country:  Singapore    
Other Details:
Languages:  eng     Pagination:  235-8     Citation Subset:  IM    
Affiliation:
Division of Congenital Heart Surgery, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, USA. mkoudieh@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / surgery
Anastomosis, Surgical
Child, Preschool
Female
Heart Defects, Congenital / surgery*
Humans
Infant
Male
Retrospective Studies
Risk Factors
Situs Inversus / surgery
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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