Document Detail

Outbreaks of gram-negative bacterial bloodstream infections traced to probable contamination of hemodialysis machines--Canada, 1995; United States, 1997; and Israel, 1997.
MedLine Citation:
PMID:  9461047     Owner:  NLM     Status:  MEDLINE    
During 1996, approximately 236,000 persons received hemodialysis in the United States; of these, an estimated 183,000 (78%) received chronic hemodialysis. Patients who receive chronic hemodialysis are at increased risk for bloodstream infections (BSIs) because of the need for repeated vascular access. Reported BSI rates for hemodialysis patients have ranged from 8.4 to 16.8 episodes per 100 patient-years, and BSI has been identified as the cause of death in 6%-18% of hemodialysis patients. Outbreaks of BSIs in hemodialysis units usually have been caused by inadequate disinfection of 1) water treatment or distribution systems and 2) reprocessed dialyzers. This report summarizes the investigations of three clusters of gram-negative bacterial BSIs at hemodialysis centers in Canada, the United States, and Israel. The findings indicate that all three outbreaks probably resulted from contamination of the waste drain ports in the same model of hemodialysis machine.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  MMWR. Morbidity and mortality weekly report     Volume:  47     ISSN:  0149-2195     ISO Abbreviation:  MMWR Morb. Mortal. Wkly. Rep.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-02-10     Completed Date:  1998-02-10     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  7802429     Medline TA:  MMWR Morb Mortal Wkly Rep     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM    
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MeSH Terms
Bacteremia / epidemiology*,  etiology
Canada / epidemiology
Disease Outbreaks
Equipment Contamination*
Gram-Negative Bacterial Infections / epidemiology*,  etiology
Israel / epidemiology
Renal Dialysis / adverse effects,  instrumentation*
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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