Document Detail

Outbreaks of Serratia marcescens infections in a cardiothoracic surgical intensive care unit.
MedLine Citation:
PMID:  1093494     Owner:  NLM     Status:  MEDLINE    
An outbreak of infections with pigmented Serratia marcescens involving 3 patients in a cardiothoracic surgical intensive care unit is reported. A respirator is thought to have been the source of pneumonia in 2 patients, and fomite spread from 1 of these is considered responsible for the induction of fatal endocarditis in the third patient. This outbreak demonstrates the rapid dissemination of a bacterial strain within the unit, several methods of dissemination, the wide variation in apparent virulence of the organism, the alterations of antibacterial host defense which made bacterial disease possible and which determined the site of infection, and the difficulties of adequate therapy. The third patient is the seventh reported with serratia infection of a prosthetic heart valve.
N M Richards; S Levitsky
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  19     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  1975 May 
Date Detail:
Created Date:  1975-07-18     Completed Date:  1975-07-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  503-13     Citation Subset:  AIM; IM    
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MeSH Terms
Anti-Bacterial Agents / pharmacology,  therapeutic use
Blood Glucose / analysis
Coronary Care Units*
Cross Infection / drug therapy,  transmission*
Disease Outbreaks*
Endocarditis, Bacterial / transmission
Enterobacteriaceae Infections / drug therapy,  transmission*
Pneumonia / transmission
Serratia marcescens* / drug effects,  isolation & purification
Ventilators, Mechanical / adverse effects
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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