Document Detail

Outbreak of hepatitis A in two federal states of Germany: bakery products as vehicle of infection.
MedLine Citation:
PMID:  16650329     Owner:  NLM     Status:  MEDLINE    
In April 2004, increased numbers of hepatitis A were noted in six neighbouring districts in Germany. Exploratory interviews showed that patients had consumed bakery products from company X where two employees had been diagnosed with hepatitis A in February. A case-control study of consumption of products of company X was carried out through telephone interviews. Altogether, 64 cases were identified. Fifty-two cases and 112 controls aged >or=16 years were included in the case-control study. In total, 46/52 cases and 37/112 controls had consumed company X products [odds ratio (OR) 15.5, 95% confidence interval (CI) 6.1-39.7]. Of these, 36/46 cases and 16/37 controls had consumed pastries (OR 4.7, 95% CI 1.8-12.3), 25/46 cases and 12/37 controls had consumed filled doughnuts (OR 2.5, 95% CI 1.0-6.1). Sequence analysis of the VP1-2A junction region indicated 100% strain homology between cases and an infected employee of company X. We recommended reinforcement of hygiene precautions, and consideration of a prolongation of compulsory work absence after post-exposure vaccination.
K Schenkel; V Bremer; C Grabe; U Van Treeck; E Schreier; M Höhne; A Ammon; K Alpers
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Publication Detail:
Type:  Journal Article     Date:  2006-05-02
Journal Detail:
Title:  Epidemiology and infection     Volume:  134     ISSN:  0950-2688     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-10-25     Completed Date:  2007-01-03     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  1292-8     Citation Subset:  IM    
Department for Infectious Diseases Epidemiology, Robert Koch-Institut, Berlin, Germany.
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MeSH Terms
Case-Control Studies
Data Collection
Disease Outbreaks*
Food Microbiology*
Foodborne Diseases
Germany / epidemiology
Hepatitis A / epidemiology*,  transmission,  virology
Hepatovirus / genetics*,  isolation & purification
Interviews as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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