Document Detail

Outbreak of aseptic meningitis by echo 4: prevalence of clinical cases among adults.
MedLine Citation:
PMID:  11209838     Owner:  NLM     Status:  MEDLINE    
Twenty five cases of meningitis occurred in urban areas surrounding a city (Modena) in Northern Italy, in the period May-July 1999. When the patients were admitted to the Infectious Diseases Division of the University of Modena and Reggio Emilia Hospital and studied by virological and serological methods, the meningitis proved to have an enteroviral origin and enterovirus ECHO 4 type was responsible for all cases of illness. An epidemiological characteristic of the enteroviral meninigitis outbreak was the adult age in 23 out of the 25 patients (mean age 24.50 +/- 7.84 years). The monthly distribution of the aseptic meningitis cases was the following: five cases occurred in May, 13 in June and seven in July. The origin of the spread of the virus infection and the reason for its sudden end remained unknown. The unusual drop in temperature which occurred in the geographic area involved in the aseptic meningitis outbreak at the beginning of August could have interfered with the slowdown in virus circulation.
M Portolani; M Pecorari; P Pietrosemoli; A Bartoletti; A M Sabbatini; M Meacci; W Gennari; E Bazzani; F Beretti; G Guaraldi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The new microbiologica     Volume:  24     ISSN:  1121-7138     ISO Abbreviation:  New Microbiol.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-07     Completed Date:  2001-04-19     Revised Date:  2011-02-25    
Medline Journal Info:
Nlm Unique ID:  9516291     Medline TA:  New Microbiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  11-5     Citation Subset:  IM    
Department of Hygiene, Microbiology and Biostatistics, Center for Diagnosis of Viral Diseases.
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MeSH Terms
Antibodies, Monoclonal / diagnostic use
Antibodies, Viral / analysis
Cercopithecus aethiops
Disease Outbreaks*
Echovirus Infections / cerebrospinal fluid,  epidemiology*,  virology*
Enterovirus B, Human / genetics,  isolation & purification*
Enzyme-Linked Immunosorbent Assay
Feces / virology
Fluorescent Antibody Technique, Indirect
Italy / epidemiology
Meningitis, Aseptic / cerebrospinal fluid,  epidemiology*,  virology*
Polymerase Chain Reaction
Vero Cells / virology
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Antibodies, Viral

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