Document Detail

Out of the mouths of babes: vocal production in infant siblings of children with ASD.
MedLine Citation:
PMID:  21039489     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Younger siblings of children with autism spectrum disorders (ASD) are at higher risk for acquiring these disorders than the general population. Language development is usually delayed in children with ASD. The present study examines the development of pre-speech vocal behavior in infants at risk for ASD due to the presence of an older sibling with the disorder.
METHODS: Infants at high risk (HR) for ASD and those at low risk, without a diagnosed sibling (LR), were seen at 6, 9, and 12 months as part of a larger prospective study of risk for ASD in infant siblings. Standard clinical assessments were administered, and vocalization samples were collected during play with mother and a standard set of toys. Infant vocal behavior was recorded and analyzed for consonant inventory, presence of canonical syllables, and of non-speech vocalizations, in a cross-sectional design. Children were seen again at 24 months for provisional diagnosis.
RESULTS: Differences were seen between risk groups for certain vocal behaviors. Differences in vocal production in the first year of life were associated with outcomes in terms of autistic symptomotology in the second year.
CONCLUSIONS: Early vocal behavior is a sensitive indicator of heightened risk for autistic symptoms in infants with a family history of ASD.
Rhea Paul; Yael Fuerst; Gordon Ramsay; Kasia Chawarska; Ami Klin
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-10-11
Journal Detail:
Title:  Journal of child psychology and psychiatry, and allied disciplines     Volume:  52     ISSN:  1469-7610     ISO Abbreviation:  J Child Psychol Psychiatry     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-18     Completed Date:  2011-08-18     Revised Date:  2014-01-14    
Medline Journal Info:
Nlm Unique ID:  0375361     Medline TA:  J Child Psychol Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  588-98     Citation Subset:  IM    
Copyright Information:
© 2010 The Authors. Journal of Child Psychology and Psychiatry © 2010 Association for Child and Adolescent Mental Health.
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MeSH Terms
Child Development Disorders, Pervasive / genetics,  psychology*
Child, Preschool
Cross-Sectional Studies
Infant Behavior / psychology*
Language Development*
Prospective Studies
Risk Factors
Siblings / psychology*
Speech Acoustics
Speech Production Measurement
Grant Support
K24 HD045576/HD/NICHD NIH HHS; P01 HD003008-397319/HD/NICHD NIH HHS; P01-03008//PHS HHS; P50 MH81756/MH/NIMH NIH HHS; R01 MH087554/MH/NIMH NIH HHS

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