Document Detail


Out in the green: biologically active metabolites produced by cyanobacteria.
MedLine Citation:
PMID:  21797171     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Dried cyanobacteria ('Spirulina') are sold as a nutraceutical for their high content of proteins, essential fatty acids and vitamins. Beyond spirulina, other genera of cyanobacteria produce interesting small molecules that could find use in nutraceutical or pharmaceutical applications. This account presents recent research efforts on antimalarial nostocarboline and the aerucyclamides, as well as on potent toxins such as cyanopeptolin 1020 and microcystins. Combinations of spectroscopic, computational, chemical and biological studies investigated the mechanism of action of these compounds. Their application potential with regard to nutraceuticals or pharmaceuticals is discussed.
Authors:
Karl Gademann
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chimia     Volume:  65     ISSN:  0009-4293     ISO Abbreviation:  Chimia (Aarau)     Publication Date:  2011  
Date Detail:
Created Date:  2011-07-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0373152     Medline TA:  Chimia (Aarau)     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  416-9     Citation Subset:  IM    
Affiliation:
University of Basel, Department of Chemistry, St. Johanns-Ring 19, CH-4056 Basel. karl.gademann@unibas.ch
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