Document Detail


Otomycosis: clinical features and treatment implications.
MedLine Citation:
PMID:  17071313     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To determine the clinical presentation, predisposing factors, complications, and treatment outcomes of otomycosis. STUDY DESIGN AND SETTING: Retrospective review of 132 patients with a clinical diagnosis of otomycosis treated from 1998 to 2004 in an academic otology practice. RESULTS: Otalgia and otorrhea were the most common presenting complaints (48%). Prior otologic procedures increase the risk of developing otomycosis. Residual disease was observed in 13% and recurrence in 15% of the subjects. The presence of a mastoid cavity was associated with higher recurrent and residual disease rates. Topical ketoconazole, cresylate otic drops, and aluminum acetate otic drops were all relatively effective with >80% resolution rate on initial application, although topical ketoconazole had a higher resolution rate and lower rate of disease recurrence. CONCLUSIONS AND SIGNIFICANCE: Otomycosis can usually be diagnosed by clinical examination and often occurs in the setting of persistent otorrhea. Complications are not uncommon but usually resolve with application of appropriate topical antifungal agents. Eradication of disease is more difficult in the presence of a mastoid cavity.
Authors:
Tang Ho; Jeffrey T Vrabec; Donald Yoo; Newton J Coker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  135     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-30     Completed Date:  2006-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  787-91     Citation Subset:  IM    
Affiliation:
Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA.
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MeSH Terms
Descriptor/Qualifier:
Acetates / administration & dosage
Administration, Topical
Adolescent
Adult
Aged
Aged, 80 and over
Antifungal Agents / administration & dosage
Child
Female
Humans
Ketoconazole / administration & dosage
Male
Middle Aged
Mycoses / diagnosis*,  drug therapy*
Otitis Externa / diagnosis*,  drug therapy*
Recurrence
Retrospective Studies
Treatment Outcome
Chemical
Reg. No./Substance:
0/Acetates; 0/Antifungal Agents; 139-12-8/aluminum acetate; 65277-42-1/Ketoconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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