| Otolith-ocular responses in patients with surgically confirmed unilateral peripheral vestibular loss. | |
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MedLine Citation:
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PMID: 14757917 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The chronic effects of unilateral peripheral vestibular loss (UPVL) are influenced by vestibular compensation. This study documents the balance-related symptoms and quantitative vestibular laboratory testing of 20 patients with surgically confirmed UPVL. Included are measures of the semicircular canal-ocular reflex, the otolith-ocular reflex, and both static and dynamic semicircular canal-otolith-interaction. This study differs from previous studies of patients with UPVL in that a large number of patients with surgically confirmed lesions were tested with three types of off-vertical axis rotation, several of the patients had anatomically preserved superior vestibular nerves, and self-perceived level of disability related to dizziness and imbalance were available. Results confirmed previously reported changes in the vestibulo-ocular reflex of patients with UPVL. Also, there was no apparent effect of anatomically preserving the superior vestibular nerve during surgical resection of vestibular schwannomas based on either subjective or objective measures of vestibular dysfunction. Further, there were no apparent correlations between subjective measures of dizziness and imbalance and objective measures of vestibulo-ocular function. These results have clinical implications for the management of patients with unilateral vestibular loss and provide insights into the process of vestibular compensation especially with respect to the otolith-ocular reflex. |
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Authors:
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Joseph M Furman; Li-Chi Hsu; Susan L Whitney; Mark S Redfern |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of vestibular research : equilibrium & orientation Volume: 13 ISSN: 0957-4271 ISO Abbreviation: J Vestib Res Publication Date: 2003 |
Date Detail:
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Created Date: 2004-02-03 Completed Date: 2004-08-03 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9104163 Medline TA: J Vestib Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 143-51 Citation Subset: IM; S |
Affiliation:
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Department of Otolaryngology, University of Pittsburgh, PA, USA. furman@pitt.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Disabled Persons Dizziness / etiology, physiopathology Female Humans Male Middle Aged Oculomotor Muscles / physiopathology Otolithic Membrane / physiopathology Reflex, Vestibulo-Ocular* Semicircular Canals / physiopathology Vestibular Diseases / complications, physiopathology* Vestibular Function Tests |
| Grant Support | |
ID/Acronym/Agency:
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DC03417/DC/NIDCD NIH HHS |
| Comments/Corrections | |
Erratum In:
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J Vestib Res. 2004;14(1):65 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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