Document Detail

Otitis media and mastoiditis due to Mycobacterium fortuitum: case report, review of four cases, and a cautionary note.
MedLine Citation:
PMID:  8783722     Owner:  NLM     Status:  MEDLINE    
Mycobacterium fortuitum is a rarely reported cause of otitis media and mastoiditis. We report such a case recently seen at our institution and review the four previously published cases of this disease entity. Amikacin is recommended in the current medical literature as empirical treatment of disease due to M. fortuitum, but the isolate from our patient showed high-level resistance to amikacin, which is rare in clinical isolates of this species; this resistance was probably related to prior treatment with topical aminoglycosides. Our patient's infection responded to a 12-month course of therapy with clarithromycin and trimethoprim-sulfamethoxazole.
R M Plemmons; C K McAllister; D A Liening; M C Garces
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  22     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1997-01-08     Completed Date:  1997-01-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1105-6     Citation Subset:  IM    
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Texas 78234, USA.
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MeSH Terms
Amikacin / therapeutic use
Anti-Bacterial Agents / therapeutic use
Cefoxitin / therapeutic use
Clarithromycin / therapeutic use
Drug Resistance, Microbial
Drug Therapy, Combination
Mastoiditis / diagnosis,  microbiology*,  therapy
Mycobacteria, Atypical* / isolation & purification
Mycobacterium Infections / diagnosis*,  drug therapy
Otitis Media / diagnosis,  drug therapy,  microbiology*
Trimethoprim-Sulfamethoxazole Combination / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 35607-66-0/Cefoxitin; 37517-28-5/Amikacin; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination; 81103-11-9/Clarithromycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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