Document Detail


Otitis externa.
MedLine Citation:
PMID:  19450296     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
INTRODUCTION: Otitis externa is thought to affect 10% of people at some stage, and can present in acute, chronic, or necrotising forms. Otitis externa may be associated with eczema of the ear canal, and is more common in swimmers, humid environments, people with absence of ear wax or with narrow ear canals, hearing-aid users, and after mechanical trauma. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of empirical and prophylactic treatments for otitis externa? We searched: Medline, Embase, The Cochrane Library, and other important databases up to October 2007 (Clinical Evidence reviews are updated periodically, please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
RESULTS: We found nine systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
CONCLUSIONS: In this systematic review we present information relating to the effectiveness and safety of the following interventions: oral antibiotics, specialist aural toilet, topical acetic acid drops or spray, topical aluminium acetate drops, topical antibacterials, topical antifungals, topical anti-infective agents, topical corticosteroids, and water exclusion.
Authors:
Daniel Hajioff; Samuel Mackeith
Related Documents :
19900576 - Technical challenges in designing post-marketing ecrfs to address clinical safety and p...
16632366 - A systematic review of lateral wedge orthotics--how useful are they in the management o...
8898036 - Systematic review of amodiaquine treatment in uncomplicated malaria.
20096216 - A practical guide to understanding systematic reviews and meta-analyses.
12368726 - Trends in aortic aneurysm surgical training for general and vascular surgery residents ...
3318986 - Facial resurfacing in xeroderma pigmentosum: are we spoiling the ship for a ha'p'orth o...
Publication Detail:
Type:  Journal Article     Date:  2008-06-26
Journal Detail:
Title:  Clinical evidence     Volume:  2008     ISSN:  1752-8526     ISO Abbreviation:  Clin Evid (Online)     Publication Date:  2008  
Date Detail:
Created Date:  2009-05-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101294314     Medline TA:  Clin Evid (Online)     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Affiliation:
Southmead Hospital, Bristol Royal Hospital for Children, Bristol, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Diabetes: managing dyslipidaemia.
Next Document:  GORD in adults.