| Osteoporotic fractures at presentation of Cushing's disease: two case reports and a literature review. | |
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MedLine Citation:
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PMID: 10963086 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Osteoporosis is a common complication of Cushing's disease/syndrome. Fractures can be the presenting manifestation. We report two cases and review 28 others from the literature. Clinical, laboratory, and absorptiometry data are reviewed; the vertebrae and ribs were the most common fracture sites, and osteoporosis reversal after treatment varied with age, gender, and symptom duration. The pathophysiology, which remains controversial, is discussed. A search for Cushing's disease/syndrome should be part of the routine evaluation of osteoporosis in children and adults, particularly men. |
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Authors:
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V Khanine; J J Fournier; E Requeda; J P Luton; F Simon; J Crouzet |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Joint, bone, spine : revue du rhumatisme Volume: 67 ISSN: 1297-319X ISO Abbreviation: Joint Bone Spine Publication Date: 2000 |
Date Detail:
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Created Date: 2000-12-04 Completed Date: 2000-12-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100938016 Medline TA: Joint Bone Spine Country: FRANCE |
Other Details:
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Languages: eng Pagination: 341-5 Citation Subset: IM |
Affiliation:
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Rheumatology Department, Sud-Francilien Hospital Center, Corbeil-Essonnes, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorptiometry, Photon Adult Alendronate / therapeutic use Bone and Bones / pathology, radiography Cushing Syndrome / complications*, pathology, radiography Fractures, Spontaneous / etiology*, pathology, radiography Humans Male Osteoporosis / drug therapy, etiology*, pathology, radiography Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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66376-36-1/Alendronate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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