Document Detail

Osteoporosis and gait and balance disturbances in older sarcopenic obese New Zealanders.
MedLine Citation:
PMID:  19436938     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Decreasing bone density and muscle mass and increasing fat mass may act synergistically to affect gait and balance in older adults.
METHODS: One hundred eighty-three older adults (age 72.7 +/- 6 years, range 56-93; body mass index 28.2 +/- 4.9, range 16.6-46.0) were recruited from a New Zealand falls prevention intervention trial. Total and appendicular skeletal muscle mass (ASM), percent fat, and bone mineralization were assessed by dual energy X-ray absorptiometry and used to characterize normal lean (NL, n = 51), sarcopenic (SS, n = 18), sarcopenic obese (SO, n = 29), and obese (OO, n = 85) phenotypes. Functional performance was assessed using timed up and go, chair stand, single leg stand, and step test. Regression models were adjusted for age, sex, medications, and physical activity.
RESULTS: Femoral neck osteoporosis was present in 22% SS, 17% SO, 12% NL, and 7% OO. Femoral neck osteoporosis with low ASM predicted poor chair stand performance (beta -3.3, standard error 1.6, p = 0.04). SO scored lowest on the chair stand (p = 0.03) and step test (p = 0.03). Higher ASM predicted faster timed up and go performance (p = 0.001).
CONCLUSIONS: Osteoporosis was prevalent in low ASM groups (SS and SO) and related to gait and balance deficits, particularly in the SO. This has implications for falls risk, fractures, and interventions.
D L Waters; L Hale; A M Grant; P Herbison; A Goulding
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-05-13
Journal Detail:
Title:  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA     Volume:  21     ISSN:  1433-2965     ISO Abbreviation:  Osteoporos Int     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-05     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100105     Medline TA:  Osteoporos Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  351-7     Citation Subset:  IM    
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, P. O. Box 913, Dunedin 9054, New Zealand.
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MeSH Terms
Accidental Falls / prevention & control,  statistics & numerical data
Aged, 80 and over
Body Composition
Body Mass Index
Bone Density
Femur Neck / physiopathology
Gait Disorders, Neurologic / etiology*
Middle Aged
Motor Activity
Obesity / complications*
Osteoporosis / complications*,  physiopathology
Postural Balance*
Sarcopenia / complications
Sensation Disorders / etiology*
Tai Ji

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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