Document Detail


Osteoporosis and gait and balance disturbances in older sarcopenic obese New Zealanders.
MedLine Citation:
PMID:  19436938     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Decreasing bone density and muscle mass and increasing fat mass may act synergistically to affect gait and balance in older adults.
METHODS: One hundred eighty-three older adults (age 72.7 +/- 6 years, range 56-93; body mass index 28.2 +/- 4.9, range 16.6-46.0) were recruited from a New Zealand falls prevention intervention trial. Total and appendicular skeletal muscle mass (ASM), percent fat, and bone mineralization were assessed by dual energy X-ray absorptiometry and used to characterize normal lean (NL, n = 51), sarcopenic (SS, n = 18), sarcopenic obese (SO, n = 29), and obese (OO, n = 85) phenotypes. Functional performance was assessed using timed up and go, chair stand, single leg stand, and step test. Regression models were adjusted for age, sex, medications, and physical activity.
RESULTS: Femoral neck osteoporosis was present in 22% SS, 17% SO, 12% NL, and 7% OO. Femoral neck osteoporosis with low ASM predicted poor chair stand performance (beta -3.3, standard error 1.6, p = 0.04). SO scored lowest on the chair stand (p = 0.03) and step test (p = 0.03). Higher ASM predicted faster timed up and go performance (p = 0.001).
CONCLUSIONS: Osteoporosis was prevalent in low ASM groups (SS and SO) and related to gait and balance deficits, particularly in the SO. This has implications for falls risk, fractures, and interventions.
Authors:
D L Waters; L Hale; A M Grant; P Herbison; A Goulding
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Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2009-05-13
Journal Detail:
Title:  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA     Volume:  21     ISSN:  1433-2965     ISO Abbreviation:  Osteoporos Int     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-05     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9100105     Medline TA:  Osteoporos Int     Country:  England    
Other Details:
Languages:  eng     Pagination:  351-7     Citation Subset:  IM    
Affiliation:
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, P. O. Box 913, Dunedin 9054, New Zealand. debra.waters@otago.ac.nz
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MeSH Terms
Descriptor/Qualifier:
Accidental Falls / prevention & control,  statistics & numerical data
Aged
Aged, 80 and over
Body Composition
Body Mass Index
Bone Density
Female
Femur Neck / physiopathology
Gait Disorders, Neurologic / etiology*
Humans
Male
Middle Aged
Motor Activity
Obesity / complications*
Osteoporosis / complications*,  physiopathology
Postural Balance*
Sarcopenia / complications
Sensation Disorders / etiology*
Tai Ji

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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