Document Detail

Osteoporosis during pregnancy and its management.
MedLine Citation:
PMID:  9759136     Owner:  NLM     Status:  MEDLINE    
Osteoporosis leading to fracture can occur during pregnancy. Bone density may be low before pregnancy due to recognised causes such as coeliac disease, osteogenesis imperfecta and previous anorexia nervosa (secondary osteoporosis). In some patients there is no identifiable cause. This condition is referred to as "pregnancy associated or pregnancy related osteoporosis"; it is not known whether pregnancy causes the osteoporosis or merely coincides with it. Typically the loss of bone leads to vertebral fracture with loss of height or pain in the hips also sometimes with fracture. Symptoms most often begin in the third trimester of the first pregnancy and improve after delivery; they do not usually recur in subsequent pregnancies. The cause is unknown and there is no specific treatment; follow up bone density measurements show that the osteoporosis slowly improves post partum. Recent research in non osteoporotic women shows that breast feeding maintains a low bone density; it is therefore contraindicated in pregnancy associated osteoporosis.
R Smith; A J Phillips
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Scandinavian journal of rheumatology. Supplement     Volume:  107     ISSN:  0301-3847     ISO Abbreviation:  Scand. J. Rheumatol. Suppl.     Publication Date:  1998  
Date Detail:
Created Date:  1998-10-21     Completed Date:  1998-10-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0400360     Medline TA:  Scand J Rheumatol Suppl     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  66-7     Citation Subset:  IM    
Department of Metabolism, Nuffield Orthopaedic Centre, Headington, Oxford, UK.
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MeSH Terms
Fractures, Spontaneous / etiology*
Osteoporosis / diagnosis,  etiology*,  therapy*
Pregnancy Complications / therapy*

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