| Osteoporosis as the presenting sign of leukemic relapse in an adolescent: case report and literature review. | |
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MedLine Citation:
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PMID: 1610848 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Osteoporosis in adolescence is rare and usually secondary to an underlying disease process whose diagnosis may be difficult to detect. Osteoporotic vertebral collapse is an uncommon presenting sign of acute lymphoblastic leukemia (ALL). We describe a 13-year-old boy with osteoporotic vertebral collapse secondary to relapse of ALL whose blood count and blood morphology were normal but whose 1,25 = (OH2) = vitamin D level was deficient. A combination of chemotherapy, calcitriol and calcitonin therapy was successful in reversing the process. His case is presented to describe the diagnostic and therapeutic issues involved. |
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Authors:
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R D Rohn; E J Werner; R L Byrd |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The Journal of adolescent health : official publication of the Society for Adolescent Medicine Volume: 13 ISSN: 1054-139X ISO Abbreviation: J Adolesc Health Publication Date: 1992 Jun |
Date Detail:
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Created Date: 1992-07-29 Completed Date: 1992-07-29 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9102136 Medline TA: J Adolesc Health Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 306-10 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Eastern Virginia Medical School, Norfolk. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Calcitonin / therapeutic use Calcitriol / blood, therapeutic use Calcium / urine Humans Hydroxyproline / urine Male Osteoporosis / diagnosis, drug therapy, etiology*, metabolism Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*, metabolism Recurrence Remission Induction |
| Chemical | |
Reg. No./Substance:
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32222-06-3/Calcitriol; 51-35-4/Hydroxyproline; 7440-70-2/Calcium; 9007-12-9/Calcitonin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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