Document Detail


Osteopaenia of the lumbar spine and femoral neck in anorexia nervosa.
MedLine Citation:
PMID:  3798090     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The bone density in the spine, femoral neck and radius in 31 outpatients with anorexia nervosa (AN) was measured by photon absorptiometry and compared with 31 age matched controls. In all bone sites measured the patients with anorexia nervosa had reduced bone mineral density (spine- control 0.91 + .10 gHA/cm2, AN 0.75 + .09 gHA/cm2; femur- control 0.87 + .09 gHA/cm2, AN 0.67 + .07 gHA/cm2; radius-control 0.41 + .04 gHA/cm2, AN 0.38 + 0.9 gHA/cm2). The mean difference between the groups was greatest in the femoral neck at 0.21 gHA/cm2 (95% CI 0.18-.024 p less than 0.001) and least at the radius 0.04 gHA/cm2 (95% CI 0.02-0.06, p less than 0.05), the lumbar spine was intermediate with a mean difference of 0.16 gHA/cm2 (95% CI 0.12-0.2 p less than 0.001). Femoral and spinal bone mineral density was positively correlated with body mass and negatively correlated with duration of amenorrhoea. Three of these patients had vertebral crush fractures which suggests that this diminution in bone density is of clinical significance.
Authors:
J Treasure; I Fogelman; G F Russell
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scottish medical journal     Volume:  31     ISSN:  0036-9330     ISO Abbreviation:  Scott Med J     Publication Date:  1986 Jul 
Date Detail:
Created Date:  1987-02-19     Completed Date:  1987-02-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2983335R     Medline TA:  Scott Med J     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  206-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anorexia Nervosa / complications*
Bone Diseases, Metabolic / etiology,  radionuclide imaging*
Bone and Bones / radionuclide imaging*
Female
Femur Neck / radionuclide imaging*
Humans
Lumbar Vertebrae / radionuclide imaging*
Middle Aged
Minerals / analysis*
Chemical
Reg. No./Substance:
0/Minerals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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