| Osteonecrosis of the femoral head in immunosuppressed patients: hip salvaging with implantation of a vascularised fibular graft. | |
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MedLine Citation:
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PMID: 7968479 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Osteonecrosis frequently occurs in patients being treated with steroids for conditions such as systemic lupus erythematosus and other collagen diseases and in renal transplant recipients. It remains an unsolved problem and can cause more disability than the underlying disease, particularly in young patients. In a series of eight young patients who received continuous corticosteroids and immunosuppressive agents, we attempted hip salvage in ten joints by implantation of a vascularised fibular graft into the necrotic femoral head. Follow-up ranged from 18 to 36 months. Joints which were operated on prior to articular surface collapse had complete restoration of normal function. In patients with more advanced lesions, surgery resulted in a painless hip, improved range of motion, and cessation of further progress of the disease. The preliminary data are considered encouraging enough to suggest that the vascularised fibular graft is an appropriate method for hip salvage in immunosuppressed patients with osteonecrosis of the femoral head. |
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Authors:
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K N Malizos; P N Soucacos; A E Beris; A B Korobilias; T A Xenakis |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Microsurgery Volume: 15 ISSN: 0738-1085 ISO Abbreviation: Microsurgery Publication Date: 1994 |
Date Detail:
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Created Date: 1994-12-28 Completed Date: 1994-12-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8309230 Medline TA: Microsurgery Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 485-91 Citation Subset: IM |
Affiliation:
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Department of Orthopaedic Surgery, School of Medicine, University of Ioannina, Greece. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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adverse effects*,
therapeutic use Adult Arthroplasty / methods Bone Transplantation / methods* Female Femur Head / surgery* Femur Head Necrosis / chemically induced, radiography, surgery* Fibula / transplantation* Follow-Up Studies Hip Joint / radiography Humans Immunosuppression / adverse effects* Kidney Transplantation / immunology Lupus Erythematosus, Systemic / drug therapy Male Middle Aged Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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