Document Detail


Osteomyelitis in children: gadolinium-enhanced MR imaging.
MedLine Citation:
PMID:  1535888     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifteen pediatric patients with biopsy- or culture-proved nonspinal osteomyelitis were studied with magnetic resonance (MR) imaging. Osteomyelitis was acute in seven patients, subacute in three, and chronic in five. Four patients had subperiosteal abscesses, one had a large associated soft-tissue abscess, and one had an intraosseous (Brodie) abscess. Areas of active inflammation had decreased marrow signal intensity on T1-weighted images, increased signal intensity on T2-weighted images, and enhancement on T1-weighted images obtained after gadopentetate dimeglumine administration (n = 10). Abscesses were rim enhancing (n = 3) or not (n = 2) with gadolinium-enhanced MR imaging. Nonenhancing areas presumably represented necrotic material. Gadolinium-enhanced MR imaging assisted in definition of the presence and extent of nonvascularized fluid collections within the bone and/or adjacent soft tissues and the extent of bone involvement in patients with chronic osteomyelitis. It also helped guide surgical debridement of intraosseous disease (n = 7) and open or percutaneous drainage of subperiosteal or soft-tissue fluid collections (n = 5).
Authors:
B C Dangman; F A Hoffer; F F Rand; E J O'Rourke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  182     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-03-23     Completed Date:  1992-03-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  743-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, Children's Hospital, Boston, MA 02115-5747.
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MeSH Terms
Descriptor/Qualifier:
Abscess / diagnosis,  microbiology
Child
Contrast Media
Drug Combinations
Female
Gadolinium / diagnostic use*
Gadolinium DTPA
Humans
Magnetic Resonance Imaging / methods*
Male
Meglumine / diagnostic use*
Organometallic Compounds / diagnostic use*
Osteomyelitis / diagnosis*,  microbiology
Pentetic Acid / diagnostic use*
Staphylococcal Infections / diagnosis*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Drug Combinations; 0/Organometallic Compounds; 6284-40-8/Meglumine; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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