Document Detail

Osteolytic lesions as a presenting sign of acute nonlymphocytic leukemia.
MedLine Citation:
PMID:  8922494     Owner:  NLM     Status:  MEDLINE    
Osteolytic lesions occur rarely in acute leukemia, especially in adults. We describe a patient with chronic myelomonocytic leukemia, in whom multiple osteolytic lesions were the presenting sign of the transformation into acute leukemia. Local irradiation to a painful lesion in the left hip resulted in transient but significant symptomatic relief with improved quality of life. We conclude that osteolytic lesions, although rare in adult acute leukemia, indicate an advanced disease state, but may respond to palliative local irradiation.
D Ben-Dayan; A Zeidman; M Djaldetti; M Mittelman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta haematologica     Volume:  96     ISSN:  0001-5792     ISO Abbreviation:  Acta Haematol.     Publication Date:  1996  
Date Detail:
Created Date:  1996-12-17     Completed Date:  1996-12-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0141053     Medline TA:  Acta Haematol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  249-50     Citation Subset:  IM    
Department of Medicine B, Hasharon Hospital, Petah-Tikva, Israel.
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MeSH Terms
Fatal Outcome
Leukemia, Myeloid, Acute / complications*,  pathology
Myelodysplastic Syndromes / complications*
Osteolysis / complications*,  radiotherapy*

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