| Osteolytic gamma heavy chain disease. | |
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MedLine Citation:
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PMID: 3115824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of gamma heavy chain disease (GHCD) with several unique features: extensive osteolytic lesions simulating advanced multiple myeloma (MM), skin involvement, under the age of 40 yr, and the appearance of a series of pathological cells with indented or lobulated nuclei. The most remarkable feature is a previously unreported extensive bone destruction. Except for the presence of this bone disease, the clinical and pathological features of the patient resembled those of GHCD rather than those of MM. We have reviewed 3 previously reported cases of GHCD associated with skeletal involvement and compared these with our case. |
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Authors:
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T Kanoh; H Nakasato |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of haematology Volume: 39 ISSN: 0902-4441 ISO Abbreviation: Eur. J. Haematol. Publication Date: 1987 Jul |
Date Detail:
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Created Date: 1987-11-10 Completed Date: 1987-11-10 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8703985 Medline TA: Eur J Haematol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 60-5 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, Faculty of Medicine, Kyoto University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cell Nucleus / ultrastructure Diagnosis, Differential Female Heavy Chain Disease / complications*, diagnosis, pathology Humans Immunoglobulin gamma-Chains Microscopy, Electron Multiple Myeloma / diagnosis Osteolysis / etiology*, pathology |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin gamma-Chains |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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