Document Detail

Osteoinvasive subungual melanoma: a case and review.
MedLine Citation:
PMID:  20214180     Owner:  NLM     Status:  MEDLINE    
Subungual melanoma is a relatively rare variant of melanoma, accounting for 0.7-3.5% of all melanoma cases in the Caucasian population. Curiously, it occurs in 8-33% of cases in black, Asian, Native American and Hispanic populations, which generally face a substantially lower risk of melanoma. Herein the authors report the case of a 69-year-old Hispanic female with a subungual melanoma of the acral lentiginous type that directly invaded the periosteum, cortex and medulla of the distal phalanx. In addition, we review published reports of acral lentiginous melanoma with osseous invasion and discuss the evidence, on a molecular level, for this entity's aggressive pattern of invasion. The review of cases is limited to those found through the PubMed search engine.
Rebecca Kleinerman; David Kriegel; Imran Amir; Patrick O Emanuel; Bryan C Markinson
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  9     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-03-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  159-63     Citation Subset:  IM    
The Mount Sinai School of Medicine, Department of Dermatology, NewYork, NY, USA.
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MeSH Terms
Bone Neoplasms / secondary*
Melanoma / pathology*
Neoplasm Invasiveness
Periosteum / pathology
Skin Neoplasms / pathology*
Toe Phalanges / pathology*

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