Document Detail

Osteoarthritis of the thumb carpometacarpal joint: correlation of ultrasound appearances to disability and treatment response.
MedLine Citation:
PMID:  23218592     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate grading of thumb carpometacarpal joint (CMCJ) osteoarthritis (OA) using ultrasound, correlating findings with disability and treatment response.
MATERIALS AND METHODS: Patients with symptomatic thumb OA attending for ultrasound-guided CMCJ steroid injection and a group of asymptomatic controls were recruited prospectively. Thumb CMCJ ultrasound was graded (osteophytes, joint-space narrowing, capsule size, and measured capsule size), and a Disabilities of the Arm Shoulder and Hand (DASH) questionnaire was completed for each patient. Symptomatic patients then underwent injection with DASH repeated 6 weeks post-treatment. Ultrasound features were correlated with the initial DASH disability score and response as defined by change in DASH 6 weeks after treatment.
RESULTS: Thirty-one patients with symptomatic OA and 37 asymptomatic controls were recruited. With the exception of osteophytes (p = 0.017), no statistically significant correlation was demonstrated between severity of ultrasound features and patient disability. However, all features demonstrated statistically significant higher grades in the symptomatic group compared to controls. Ultrasound grading did not have statistical correlation with treatment response.
CONCLUSION: No correlation was found between the majority of ultrasound features and the clinical severity of OA or likely response to treatment. However, these features are significantly more common in the symptomatic population.
P I Mallinson; J K Tun; R D Farnell; D A Campbell; P Robinson
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-12-05
Journal Detail:
Title:  Clinical radiology     Volume:  68     ISSN:  1365-229X     ISO Abbreviation:  Clin Radiol     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-04-15     Completed Date:  2013-06-04     Revised Date:  2013-08-28    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  461-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
Department of Musculoskeletal Radiology, Leeds Teaching Hospitals NHS Trust, UK.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Analysis of Variance
Carpometacarpal Joints / drug effects,  ultrasonography*
Disabled Persons*
Middle Aged
Osteoarthritis / complications,  drug therapy*,  ultrasonography*
Pain / drug therapy,  etiology
Pain Measurement / methods,  statistics & numerical data
Prospective Studies
Severity of Illness Index
Treatment Outcome
Ultrasonography, Interventional / methods*
Reg. No./Substance:
0/Adrenal Cortex Hormones
Comment In:
Clin Radiol. 2013 Aug;68(8):869   [PMID:  23692806 ]
Clin Radiol. 2013 Aug;68(8):868   [PMID:  23692805 ]

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