Document Detail


Osteoarthritis of the spine: the facet joints.
MedLine Citation:
PMID:  23147891     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Osteoarthritis (OA) of the spine involves the facet joints, which are located in the posterior aspect of the vertebral column and, in humans, are the only true synovial joints between adjacent spinal levels. Facet joint osteoarthritis (FJ OA) is widely prevalent in older adults, and is thought to be a common cause of back and neck pain. The prevalence of facet-mediated pain in clinical populations increases with increasing age, suggesting that FJ OA might have a particularly important role in older adults with spinal pain. Nevertheless, to date FJ OA has received far less study than other important OA phenotypes such as knee OA, and other features of spine pathoanatomy such as degenerative disc disease. This Review presents the current state of knowledge of FJ OA, including relevant anatomy, biomechanics, epidemiology, and clinical manifestations. We present the view that the modern concept of FJ OA is consonant with the concept of OA as a failure of the whole joint, and not simply of facet joint cartilage.
Authors:
Alfred C Gellhorn; Jeffrey N Katz; Pradeep Suri
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2012-11-13
Journal Detail:
Title:  Nature reviews. Rheumatology     Volume:  9     ISSN:  1759-4804     ISO Abbreviation:  Nat Rev Rheumatol     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-01     Completed Date:  2013-09-30     Revised Date:  2014-05-08    
Medline Journal Info:
Nlm Unique ID:  101500080     Medline TA:  Nat Rev Rheumatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  216-24     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Back Pain / diagnosis,  epidemiology
Biomechanical Phenomena
Cervical Vertebrae / physiopathology
Diagnostic Imaging / methods
Female
Humans
Lumbar Vertebrae / physiopathology
Male
Middle Aged
Neck Pain / diagnosis,  epidemiology
Osteoarthritis / diagnosis*,  epidemiology*,  therapy
Pain Measurement
Prevalence
Prognosis
Risk Assessment
Severity of Illness Index
Spinal Diseases / diagnosis*,  epidemiology*,  therapy
Treatment Outcome
Zygapophyseal Joint / pathology*
Grant Support
ID/Acronym/Agency:
P60 AR 47782/AR/NIAMS NIH HHS; P60 AR047782/AR/NIAMS NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Voltage-driven transport of ions and DNA through nanocapillaries.
Next Document:  Role of peripheral nerve fibres in acute and chronic inflammation in arthritis.