Document Detail

Osteoarthritis? Ochronotic arthritis! A case study and review of the literature.
MedLine Citation:
PMID:  19381613     Owner:  NLM     Status:  MEDLINE    
Alkaptonuria is a rare disease in which the body does not have enough of an enzyme called homogentisic acid oxidase. Osteoarthritis is the most common degenerative joint disease. Ochronotic arthritis which resulting from the deposition of oxidized homogentisic acid within the connective tissues of peripheral joints has clinical feature that resembles those of osteoarthritis, but it has a unique manifestation. We reported a case of a patient of ochronotic arthritis, arthroscopic findings showed large areas of darkly pigmented full-thickness cartilage defects in the right knee, the whole meniscal parenchymatous tissue was also darkly pigmented. Histological investigation proved to be ochronosis.
Bao Hui Zhao; Bai Cheng Chen; De Cheng Shao; Qi Zhang
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-04-21
Journal Detail:
Title:  Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA     Volume:  17     ISSN:  1433-7347     ISO Abbreviation:  Knee Surg Sports Traumatol Arthrosc     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-25     Completed Date:  2009-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314730     Medline TA:  Knee Surg Sports Traumatol Arthrosc     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  778-81     Citation Subset:  IM    
Department of Joint Surgery, Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, 050051, Shijiazhuang, Hebei, China.
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MeSH Terms
Alkaptonuria / complications*
Diagnosis, Differential
Knee Joint*
Middle Aged
Ochronosis / diagnosis*,  etiology,  pathology
Osteoarthritis, Knee / diagnosis*

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