| Osmotic complications of low-molecular-weight dextran therapy in free flap surgery. | |
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MedLine Citation:
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PMID: 1375307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Low-molecular-weight dextran is utilized by many microsurgeons after free tissue transfer for its beneficial effects on the microcirculation. While it is generally felt to have a low rate of complications, severe complications secondary to dextran's osmotic effects may occur. We report here on two cases in which therapy with low-molecular-weight dextran was strongly implicated as a causative factor in major complications. These cases and their background are reviewed. Guidelines for the safe administration of this agent in patients post free-tissue transfer are discussed. |
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Authors:
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C K Hardin; W C Kirk; W C Pederson |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Microsurgery Volume: 13 ISSN: 0738-1085 ISO Abbreviation: Microsurgery Publication Date: 1992 |
Date Detail:
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Created Date: 1992-06-25 Completed Date: 1992-06-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8309230 Medline TA: Microsurgery Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 36-8 Citation Subset: IM |
Affiliation:
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Division of Plastic Surgery, Wilford Hall U.S.A.F. Medical Center, Lackland Air Force Base, San Antonio, Texas. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Dextrans / administration & dosage, adverse effects* Female Foot / surgery* Humans Hyperkalemia / chemically induced Kidney Failure, Acute / chemically induced Male Middle Aged Molecular Weight Muscles / transplantation* Osmosis Pseudotumor Cerebri / chemically induced Surgical Flaps* / methods |
| Chemical | |
Reg. No./Substance:
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9004-54-0/Dextrans |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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