Document Detail

Oscillatory dynamics in intercellular communication.
MedLine Citation:
PMID:  1964557     Owner:  NLM     Status:  MEDLINE    
The role of biological rhythms in the control of intercellular communication is briefly reviewed. In particular, pulsatile cAMP signaling in the slime mold, Dictyostelium discoideum, the pulsatile release of the hormone GnRH in higher animals, and cytosolic calcium oscillations are discussed, with special reference to underlying molecular mechanisms. It is pointed out that there exists an optimal pattern of periodic stimulation by hormones and that frequency encoding has some advantages in comparison with amplitude encoding, especially concerning the accuracy of control.
A Goldbeter; Y Li; G Dupont
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Biomedica biochimica acta     Volume:  49     ISSN:  0232-766X     ISO Abbreviation:  Biomed. Biochim. Acta     Publication Date:  1990  
Date Detail:
Created Date:  1991-05-08     Completed Date:  1991-05-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8304435     Medline TA:  Biomed Biochim Acta     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  935-40     Citation Subset:  IM    
Faculté des Sciences, Université Libre de Bruxelles, Belgium.
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MeSH Terms
Biological Clocks*
Calcium / physiology
Cell Communication*
Cyclic AMP / physiology
Dictyostelium / physiology*
Signal Transduction*
Reg. No./Substance:
60-92-4/Cyclic AMP; 7440-70-2/Calcium

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